LUC7L3 and RNPS1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		LUC7L3	RNPS1
Description		LUC7 like 3 pre-mRNA splicing factor	RNA binding protein with serine rich domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U1 SnRNP Nuclear Speck U2-type Prespliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	MRNA Splice Site Selection RNA Splicing	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Mild to moderate chronic kidney disease ( 31178898)
Interacting Genes		9 interacting genes: CLK1 ITSN2 MLH1 RNPS1 SRPK1 SRPK2 SRSF1 TLR10 YWHAG	62 interacting genes: ABI2 CCNL1 CHERP CLK2 CLK3 DVL2 ELOA2 FAM81B GOLGA6L9 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKAPD1 NKTR PICK1 PIN1 PNN PRPF38A PSTPIP1 RBM8A RBMY1F RBMY1J SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF11 SRSF3 SRSF4 SRSF6 SRSF7 SRSF9 STX11 TAF2 TBC1D26 TRA2A TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YTHDC1 YWHAB YWHAG ZBTB14 ZNF165 ZNF286A ZNF345 ZNF394 ZNF41 ZNF473 ZNF490 ZNF660 ZRANB1 ZSCAN30
Entrez ID		51747	10921
HPRD ID		16759	07341
Ensembl ID		ENSG00000108848	ENSG00000205937
Uniprot IDs		A8K3C5 J3KPP4 O95232 Q86Y74	D3DU92 H3BMS0 Q15287
PDB IDs			4A8X
Enriched GO Terms of Interacting Partners?
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