CD244 and ACO2

Data Source:
BioGRID (affinity chromatography technology)

		CD244	ACO2
Description		CD244 molecule	aconitase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding Signaling Receptor Activity MHC Class I Protein Binding	Aconitate Hydratase Activity Iron Ion Binding Citrate Dehydratase Activity 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Adaptive Immune Response Natural Killer Cell Activation Involved In Immune Response Signal Transduction Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Leukocyte Migration Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Granzyme B Production	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle Citrate Metabolic Process
Pathways		Cell surface interactions at the vascular wall	Mitochondrial protein import Citric acid cycle (TCA cycle)
Drugs			Isocitric Acid 4-Hydroxy-Aconitate Ion Alpha-Methylisocitric Acid Aconitate Ion Tricarballylic acid
Diseases
GWAS		Blood protein levels ( 28240269) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) White blood cell count ( 32888494)	Adult body size ( 32376654) Asthma ( 32296059) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: ARHGEF7 CD247 CD48 LAT SH2D1B	5 interacting genes: APP ATXN1L C5AR2 CDC42 SUMO4
Entrez ID		51744	50
HPRD ID		16121	00012
Ensembl ID		ENSG00000122223	ENSG00000100412
Uniprot IDs		Q9BZW8	Q99798
PDB IDs
Enriched GO Terms of Interacting Partners?
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