MBIP and EPB41L3

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		MBIP	EPB41L3
Description		MAP3K12 binding inhibitory protein 1	erythrocyte membrane protein band 4.1 like 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Nucleolus Cytosol	Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Cell Junction Axolemma Paranode Region Of Axon Juxtaparanode Region Of Axon
	Molecular Function	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein-membrane Anchor Activity
	Biological Process	Osmosensory Signaling MAPK Cascade Histone H3 Acetylation	Regulation Of Cell Growth Protein Localization To Paranode Region Of Axon Apoptotic Process Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Actomyosin Structure Organization Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane
Pathways		HATs acetylate histones	Neurexins and neuroligins
Drugs
Diseases
GWAS		Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335)	Cerebral amyloid deposition (PET imaging) ( 26252872) Chronic kidney disease ( 31152163) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate (creatinine) ( 28452372) Optic nerve head parameters (multi-trait analysis) ( 31798171) Sleep duration ( 25469926) Social communication problems ( 24564958) Thyroid nodules ( 30099483) Vertical cup-disc ratio ( 31798171)
Interacting Genes		44 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SMARCB1 STX11 TGIF2LY TRIM55 TRIM63 TXLNA TXLNB VPS28 VTA1 WDR5	19 interacting genes: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 HSPB1 IGSF21 MBIP PAXIP1 PSEN1 SPANXN2 SPTBN1 TCF4 UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		51562	23136
HPRD ID		14368	05622
Ensembl ID		ENSG00000151332	ENSG00000082397
Uniprot IDs		B2RCV0 Q9NS73	A0A0A0MRA8 A8K968 Q9Y2J2
PDB IDs			2HE7 3BIN 6IBE
Enriched GO Terms of Interacting Partners?
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