NELFCD and ENDOV

Data Source:
HPRD (two hybrid)

		NELFCD	ENDOV
Description		negative elongation factor complex member C/D	endonuclease V
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GO Annotations	Cellular Component	Nucleoplasm Membrane NELF Complex	Nucleolus Cytoplasm Cytoplasmic Stress Granule
	Molecular Function	RNA Binding Protein Binding	Magnesium Ion Binding DNA Binding Single-stranded RNA Binding Protein Binding Endodeoxyribonuclease Activity, Producing 5'-phosphomonoesters Endoribonuclease Activity, Producing 5'-phosphomonoesters
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription	DNA Repair RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 27863252)	Total intracranial volume ( 31530798)
Interacting Genes		21 interacting genes: AAMP AR ARAF ARPC4 CACNA1A CDSN DNAJA1 ENDOV EPRS1 FRMD5 GSTM4 HDAC11 MTA1 NELFA NELFB PRMT5 SERF2 SMAD4 TXK UBE3A ZNF638	2 interacting genes: NELFCD PRPSAP2
Entrez ID		51497	284131
HPRD ID		16096	08758
Ensembl ID		ENSG00000101158	ENSG00000173818
Uniprot IDs		H0UI80 Q8IXH7	Q6ZW30 Q8N8Q3
PDB IDs		5L3X 6GML	4NSP 6OZE
Enriched GO Terms of Interacting Partners?
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