AMOTL2 and BYSL

Data Source:
BioGRID (two hybrid)

		AMOTL2	BYSL
Description		angiomotin like 2	bystin like
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Cytoplasmic Vesicle Recycling Endosome	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Membrane Preribosome, Small Subunit Precursor Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	Protein Binding	RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation RRNA Processing Cell Population Proliferation Ribosome Biogenesis Regulation Of Protein Localization To Nucleolus
Pathways		Signaling by Hippo	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)	Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Menarche (age at onset) ( 27182965 25231870) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Red blood cell count ( 20139978)
Interacting Genes		91 interacting genes: AMOT BFSP2 BLZF1 BRMS1L BYSL CARD9 CCDC185 CCDC196 CCDC57 CCHCR1 CDC37 CDR2 CHCHD3 CINP CYTH4 DAXX DDIT3 DTNB DYNLL1 DZIP1L EIF4E2 FAM184A FAM90A1 FBXO7 FCRL5 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KIF9 KRT1 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 L3MBTL2 LMNB2 LMO3 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MORF4L2 MPP1 MTMR6 MTNR1A MYO5B NDC80 NF2 NFIL3 NME7 NTAQ1 PIBF1 PPP2CA PPP2R1A PRKAA2 PRPF18 PSMC3 RAD51D RALBP1 RASAL3 RASSF5 RNF20 RNF40 RNF8 SAAL1 SH3RF2 SMARCE1 SOGA1 SP100 SPAG5 SPOP SPP1 TCEA2 THRA TMCC2 TNKS2 TRAF2 TRIM27 TSGA10IP YES1 ZBED1 ZBTB16 ZGPAT	139 interacting genes: AIMP2 AMOTL2 APP ATP5F1B AXIN2 BEND7 BFSP1 BHLHE40 C1orf94 CAVIN4 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 DVL2 EAPP EMD EPS8 FAM228A FAM9B FCHO1 FXR1 FXR2 GAS8 GMCL1 GOLGA2 GOLGA6L9 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 IKZF3 JRK KATNAL1 KIFC3 KLHL2 KLHL6 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LDOC1 LHX3 LMNA LMO1 LMO2 LONRF1 LTV1 LZTS1 LZTS2 MB21D2 MCIDAS MEOX1 MEOX2 MID1 MID2 MIPOL1 MKRN1 MRFAP1L1 MTUS2 NECAB2 NF2 OLIG3 OSBPL3 PDE4DIP PHC2 PICK1 PIH1D1 PNMA1 PNMA2 PRICKLE1 PSMC6 RACGAP1 RACK1 RALY RALYL RBAK RP9 RUBCN SMN1 SMN2 SNW1 SSX2IP STX11 TBC1D26 TEKT1 TFIP11 THAP1 TLE5 TNIP1 TRAF2 TRAF4 TRAK1 TRIM14 TRIM27 TRIM37 TRIM38 TRIM41 TRIM54 TRIM55 TRIP6 TRO TROAP UBE2H USH1G VIM VPS37B VPS52 WASF3 WTAP ZBTB14 ZBTB8A ZC2HC1C ZFP64 ZMAT5 ZNF212 ZNF286A ZNF426 ZNF438 ZNF48 ZNF655 ZNF668 ZNF71 ZNF835 ZRANB1 ZSCAN22
Entrez ID		51421	705
HPRD ID		16485	04848
Ensembl ID		ENSG00000114019	ENSG00000112578
Uniprot IDs		Q9Y2J4	Q13895
PDB IDs			6G18 6G4S 6G4W
Enriched GO Terms of Interacting Partners?
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