CDK18 and EYA2

  • Data Source:
  • BioGRID (two hybrid)

CDK18

EYA2

Description cyclin dependent kinase 18 EYA transcriptional coactivator and phosphatase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease in type 1 diabetes ( 29695241)
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
  • Allergic rhinitis ( 31361310)
  • Asthma ( 32296059)
  • Brain volume in infants (intracranial brain volume) ( 28763065)
  • Coffee consumption ( 31046077)
  • FEV1 ( 30804560)
  • Heel bone mineral density ( 30598549 28869591)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Lung function (FVC) ( 30061609 30804560)
  • Non-del(5q) myelodysplastic syndromes ( 31738830)
  • Peak expiratory flow ( 30804560)
  • Reticulocyte count ( 32888494)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Triglyceride levels ( 32203549 32154731)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Type 2 diabetes ( 30054458 30297969)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes 56 interacting genes: AK8 APP BLZF1 CBY2 CCDC102B CCDC125 CCDC85B CCDC88B CCND3 CCNDBP1 CCNK CEP76 EYA2 FSD2 GOLGA2 GOLGA6L9 GORASP2 HAP1 HMBOX1 HOMER3 HOOK2 INCA1 KIFC3 KRT15 KRT16 KRT31 KRT34 KRT40 KRT75 KRT86 LZTS2 MAD1L1 MID2 MIPOL1 MTUS2 NUTM1 PIBF1 PNMA1 PPFIA1 RABEP1 REL SEC23A TRAF1 TRAF2 TRIM27 TRIM50 TRIM54 TSGA10 TTC23 VPS28 VPS52 YWHAQ ZNF426 ZNF438 ZNF774 ZRANB1 35 interacting genes: AATK BAG3 CATSPER1 CDK18 DMRTB1 DTX2 DUSP21 ENKD1 FAM214B GNAI2 GNAZ HGS IQUB LGALS4 MED25 PATZ1 PAX9 PIN1 POGZ RBPMS RFX2 ROR2 SIX1 SIX4 SNRPC SPG21 SUOX TEKT4 TEKT5 TFG TLE5 TRAF4 TRAPPC6A TSSK3 VPS37C
Entrez ID 5129 2139
HPRD ID 01354 09041
Ensembl ID ENSG00000117266 ENSG00000064655
Uniprot IDs A0A024R980 A0A024R996 Q07002 Q59G02 E7ETN2 O00167
PDB IDs 3GEB 3HB0 3HB1 4EGC 5ZMA
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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