SHISA5 and DESI1

Data Source:
BioGRID (two hybrid)

		SHISA5	DESI1
Description		shisa family member 5	desumoylating isopeptidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Membrane Nuclear Membrane	Nucleus Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Importin-alpha Family Protein Binding SUMO-specific Isopeptidase Activity
	Biological Process	Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Post-translational Protein Modification Cellular Protein Metabolic Process	Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Modification By Small Protein Removal
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: ARL6IP1 COPS5 DESI1 HNRNPD SCAND1 SGTA SGTB TP53 TVP23B	33 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RNF4 RPS27A SHISA4 SHISA5 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLN2 UBQLNL UHRF2 XPO1 ZBTB46
Entrez ID		51246	27351
HPRD ID		06290	18590
Ensembl ID		ENSG00000164054	ENSG00000100418
Uniprot IDs		A0A024R2S8 Q8N114	Q6ICB0
PDB IDs			3EBQ
Enriched GO Terms of Interacting Partners?
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