PIGP and FIS1

Data Source:
BioGRID (two hybrid)

		PIGP	FIS1
Description		phosphatidylinositol glycan anchor biosynthesis class P	fission, mitochondrial 1
Image		No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Mitochondrion Peroxisome Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Mitochondrial Outer Membrane Protein-containing Complex
	Molecular Function	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Protein Binding Identical Protein Binding
	Biological Process	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane	Mitochondrial Fission Autophagy Of Mitochondrion Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Positive Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of ATP Metabolic Process Negative Regulation Of Fatty Acid Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)	Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS			Rheumatoid arthritis ( 30891314)
Interacting Genes		17 interacting genes: C1GALT1 DHRSX FIS1 IER3IP1 ITGAM LHFPL3 NINJ2 PLP1 PLP2 PTPN1 SCAMP5 SMAGP THSD7B TMEM107 TMEM19 TMEM229B UBIAD1	30 interacting genes: A2M ABHD6 APH1A BCAP31 CREB3 DNM1L EBP ERGIC3 FAM209A FAM210B FFAR2 JAGN1 KASH5 KCNJ6 MARCHF5 MMGT1 NOS3 PIGP RNASEK SCN3B SLC10A6 SLC14A1 SLC22A1 SLC22A2 SPCS1 TBC1D15 TMEM14B TMPPE UBC VKORC1
Entrez ID		51227	51024
HPRD ID		05806	12352
Ensembl ID		ENSG00000185808	ENSG00000214253
Uniprot IDs		P57054	Q9Y3D6
PDB IDs			1NZN 1PC2
Enriched GO Terms of Interacting Partners?
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