RLIM and REXO1

Data Source:
BioGRID (enzymatic study)

		RLIM	REXO1
Description		ring finger protein, LIM domain interacting	RNA exonuclease 1 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Transcription Repressor Complex	Nucleus Nucleoplasm Nuclear Body
	Molecular Function	Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleic Acid Binding Exonuclease Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Random Inactivation Of X Chromosome Regulation Of Dosage Compensation By Inactivation Of X Chromosome	Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Body mass index ( 29273807) Essential hypertension (time to event) ( 32589924) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		30 interacting genes: BRF1 ESR1 ISL1 LDB1 LDB2 LHX1 LHX2 LHX3 LIMK1 LMO2 LNX2 MDM2 PDLIM1 REXO1 RPS14 SIN3A SMAD7 SMURF2 SNX17 SS18L1 STAT6 TERF1 TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2K	4 interacting genes: ELOA PAFAH1B2 RLIM TCEA1
Entrez ID		51132	57455
HPRD ID		02304	15478
Ensembl ID		ENSG00000131263	ENSG00000079313
Uniprot IDs		Q9NVW2	Q8N1G1
PDB IDs		6W7Z 6W9A 6W9D
Enriched GO Terms of Interacting Partners?
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