PDCL and CCT3

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		PDCL	CCT3
Description		phosducin like	chaperonin containing TCP1 subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cilium	Zona Pellucida Receptor Complex Cytosol Chaperonin-containing T-complex Cytoskeleton Microtubule Cell Body Extracellular Exosome
	Molecular Function	Protein Binding Protein-containing Complex Binding	RNA Binding Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Protein Folding Signal Transduction Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Cell Projection Organization Positive Regulation Of Smoothened Signaling Pathway Negative Regulation Of Protein Refolding Heterotrimeric G-protein Complex Assembly	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Pore Complex Assembly Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester Artenimol
Diseases
GWAS		Obesity-related traits ( 23251661)	Basophil count ( 32888494) Glycated hemoglobin levels ( 24647736) Household income (MTAG) ( 31844048) Mean corpuscular hemoglobin concentration ( 20139978) Mean corpuscular volume ( 29403010) Red blood cell count ( 29403010) Red cell distribution width ( 32888494) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		11 interacting genes: CCT3 CCT5 GNB1 GNGT1 GRK2 IKBKG LRRK2 MFHAS1 MRPL11 PSMC5 TCP1	24 interacting genes: BUD31 DEPDC5 EIF2B2 ERBB2 FANCA GEMIN4 HNRNPA0 HSPA8 LINC01554 LNX2 MAPK6 MIPOL1 PAFAH1B2 PDCL POLR1C PTEN RAF1 SH3BP4 SUMO2 UBE2Z VAV2 VHL XRCC6 ZNRD2
Entrez ID		5082	7203
HPRD ID		05108	08969
Ensembl ID		ENSG00000136940	ENSG00000163468
Uniprot IDs		Q13371	B3KX11 P49368 Q59H77
PDB IDs			6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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