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DELEC1 and CRY2
Data Source:
BioGRID
(two hybrid)
DELEC1
CRY2
Description
deleted in esophageal cancer 1
cryptochrome circadian regulator 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Cytoplasm
Cytosol
Nuclear Speck
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
Damaged DNA Binding
Single-stranded DNA Binding
Deoxyribodipyrimidine Photo-lyase Activity
DNA (6-4) Photolyase Activity
Protein Binding
Blue Light Photoreceptor Activity
Phosphatase Binding
FAD Binding
Biological Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Transcription By RNA Polymerase II
Photoreactive Repair
Circadian Rhythm
Response To Light Stimulus
Blue Light Signaling Pathway
Response To Activity
Protein-chromophore Linkage
Negative Regulation Of Phosphoprotein Phosphatase Activity
Circadian Regulation Of Gene Expression
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Negative Regulation Of Transcription, DNA-templated
Regulation Of Sodium-dependent Phosphate Transport
Negative Regulation Of Glucocorticoid Receptor Signaling Pathway
Pathways
Circadian Clock
Drugs
Diseases
GWAS
Alzheimer's disease or fasting glucose levels (pleiotropy) (
30805717
)
Axial length (
24144296
)
Fasting blood glucose (
20081858
22581228
)
Fasting blood glucose (BMI interaction) (
22581228
)
Glycemic traits (pleiotropy) (
31021400
)
Triglyceride levels (
32203549
)
Type 2 diabetes (
30297969
)
Visceral fat (
22589738
)
Interacting Genes
29 interacting genes:
ARNTL
BHLHE41
CIPC
CLOCK
CRY1
CRY2
CSNK1E
CSNK2A1
CSNK2A2
CSNK2B
EZH2
FBXL15
GSK3B
NFIL3
NONO
NPAS2
NR1D2
PER1
PER2
PPP1CA
PPP1CB
PPP1CC
PPP2CA
PPP2R1A
PPP2R1B
PPP2R5D
PPP2R5E
RORB
RORC
50 interacting genes:
ATXN1
BHLHE41
BRCA1
CLOCK
CTBP1
CYSRT1
DELEC1
EZH2
KLHL6
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-7
KRTAP10-8
KRTAP19-6
KRTAP4-2
KRTAP5-1
KRTAP5-2
KRTAP5-4
KRTAP5-7
KRTAP5-9
KRTAP6-3
KRTAP9-8
LMNA
MID1
MTUS2
NADK
NBPF19
NOTCH2NLA
NPAS2
PDE9A
PER1
PER2
PER3
PICK1
PPP2R1B
PPP2R5D
PPP2R5E
PPP5C
PTGER4
SBK3
SDCBP2
STK11
TIMELESS
TRAF1
TRAF2
TTC1
VWC2
XRN2
ZBTB42
Entrez ID
50514
1408
HPRD ID
16068
07226
Ensembl ID
ENSG00000173077
ENSG00000121671
Uniprot IDs
A0A0D2X7Z3
A2I2P1
Q49AN0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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