PAFAH1B2 and CCT3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAFAH1B2	CCT3
Description		platelet activating factor acetylhydrolase 1b catalytic subunit 2	chaperonin containing TCP1 subunit 3
Image
GO Annotations	Cellular Component	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Zona Pellucida Receptor Complex Cytosol Chaperonin-containing T-complex Cytoskeleton Microtubule Cell Body Extracellular Exosome
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity	RNA Binding Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy Neutrophil Degranulation	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Pore Complex Assembly Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester Artenimol
Diseases
GWAS		Adult body size ( 32376654) Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)	Basophil count ( 32888494) Glycated hemoglobin levels ( 24647736) Household income (MTAG) ( 31844048) Mean corpuscular hemoglobin concentration ( 20139978) Mean corpuscular volume ( 29403010) Red blood cell count ( 29403010) Red cell distribution width ( 32888494) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		19 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1	24 interacting genes: BUD31 DEPDC5 EIF2B2 ERBB2 FANCA GEMIN4 HNRNPA0 HSPA8 LINC01554 LNX2 MAPK6 MIPOL1 PAFAH1B2 PDCL POLR1C PTEN RAF1 SH3BP4 SUMO2 UBE2Z VAV2 VHL XRCC6 ZNRD2
Entrez ID		5049	7203
HPRD ID		03940	08969
Ensembl ID		ENSG00000168092	ENSG00000163468
Uniprot IDs		P68402 V9HW44	B3KX11 P49368 Q59H77
PDB IDs		1VYH	6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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