GPX8 and YIF1A

Data Source:
BioGRID (two hybrid)

		GPX8	YIF1A
Description		glutathione peroxidase 8 (putative)	Yip1 interacting factor homolog A, membrane trafficking protein
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Integral Component Of Membrane	Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Peroxidase Activity Glutathione Peroxidase Activity Protein Binding	Protein Binding
	Biological Process	Cellular Response To Oxidative Stress Cellular Oxidant Detoxification	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport IRE1-mediated Unfolded Protein Response
Pathways		Detoxification of Reactive Oxygen Species	XBP1(S) activates chaperone genes
Drugs		Glutathione Glutathione disulfide
Diseases
GWAS		Cocaine dependence ( 31212010)	Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		152 interacting genes: - AGTRAP AIG1 ALG8 APOC3 APOD AQP1 AQP2 AQP3 ASGR1 ASPH BCL2L2 BET1 BIK BMP10 BNIP2 BTN2A2 C14orf180 C1GALT1 CACNG1 CD302 CD53 CD81 CDIPT CDS2 CFHR5 CHST1 CLDN19 CLEC1A CLEC2A CMTM5 CNIH1 CNIH3 COL4A5 COL8A2 CORIN CYB561 CYB561A3 CYB561D2 DNAJC30 DOLK EDDM3B ERG28 ERO1A FA2H FAM3C FAXDC2 GET3 GOSR2 GPR151 GPR37L1 GRINA GYPA HHATL HMOX2 IGFBP5 INSIG2 KIR2DL3 KLRG1 LAPTM4B LEPROTL1 LHFPL5 LNPEP LPAR3 MAN2B2 MARCHF2 MARCHF5 MFSD5 MFSD6 MGST2 MGST3 MIP MMD MYADML2 NEU1 NINJ1 NIPAL3 NKG7 NRM OCLN PAEP PAQR5 PAQR6 PGAP2 PLLP PLN PLP2 PLPP4 PLPP6 PNLIPRP1 PRB1 RBFA RND1 RTP2 SCARB2 SCARF1 SCD SEC22B SELENOK SERINC1 SERINC2 SERP1 SERTM1 SFTPC SGMS2 SLC13A3 SLC30A3 SLC34A3 SLC35A1 SLC35B4 SLC41A2 SMAGP SNORC ST6GAL2 STX3 STX8 SYT15 TF THBD TIMMDC1 TM4SF4 TMBIM6 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14B TMEM19 TMEM218 TMEM229B TMEM243 TMEM254 TMEM42 TMEM50B TMEM60 TMEM86B TMEM97 TMPRSS4 TMUB2 TRAM1L1 TSPAN33 UNC50 UPK1B VAMP3 VAMP4 VAMP5 VKORC1L1 VSTM1 VTI1B YIF1A YIPF6 ZDHHC22	72 interacting genes: APOA5 AQP6 BNIP2 C4orf3 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 HSD17B11 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35C2 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27
Entrez ID		493869	10897
HPRD ID		17416	06755
Ensembl ID		ENSG00000164294	ENSG00000174851
Uniprot IDs		B4DPY0 E7ETY7 J3KNB5 Q8TED1	A6NGW1 A8K509 O95070
PDB IDs		3CYN 3KIJ
Enriched GO Terms of Interacting Partners?
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