NUP98 and NFX1

Data Source:
BioGRID (fluorescent resonance energy transfer)

		NUP98	NFX1
Description		nucleoporin 98 and 96 precursor	nuclear transcription factor, X-box binding 1
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Body Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Intracellular Membrane-bounded Organelle Host Cell Nuclear Pore Nuclear Basket Ribonucleoprotein Complex	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane
	Molecular Function	Transcription Coactivator Activity MRNA Binding Transporter Activity Protein Binding Nuclear Localization Sequence Binding Serine-type Peptidase Activity Structural Constituent Of Nuclear Pore Promoter-specific Chromatin Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Proteolysis Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Pore Organization Viral Process Protein Sumoylation Viral Transcription Positive Regulation Of Transcription, DNA-templated Positive Regulation Of MRNA Splicing, Via Spliceosome Nuclear Pore Complex Assembly Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Inflammatory Response Viral Process Protein Ubiquitination Negative Regulation Of MHC Class II Biosynthetic Process Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS		Malaria ( 31844061) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736)
Interacting Genes		19 interacting genes: APC CREBBP CSNK2A1 EP300 HDAC1 IPO5 KPNB1 NFX1 NUP133 NUP155 NUP62 NUP88 NXF1 RAE1 RCC1 SEC13 TNPO1 TNPO2 TPR	9 interacting genes: ELAVL4 MAML3 NUP153 NUP214 NUP62 NUP98 RANBP2 UBC UBE2N
Entrez ID		4928	4799
HPRD ID		03012	11936
Ensembl ID		ENSG00000110713	ENSG00000086102
Uniprot IDs		P52948	Q12986
PDB IDs		1KO6 2Q5X 2Q5Y 3MMY 4OWR 5A9Q 6BZM
Enriched GO Terms of Interacting Partners?
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