ATP2B1 and DAO

Data Source:
BioGRID (two hybrid)

		ATP2B1	DAO
Description		ATPase plasma membrane Ca2+ transporting 1	D-amino acid oxidase
Image
GO Annotations	Cellular Component	Immunological Synapse Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Dendritic Spine Membrane Neuronal Cell Body Membrane Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Presynaptic Active Zone Membrane	Cytoplasm Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol
	Molecular Function	Calcium Transmembrane Transporter Activity, Phosphorylative Mechanism Protein Binding Calmodulin Binding ATP Binding Calcium Ion Transmembrane Transporter Activity ATPase Activity ATPase-coupled Cation Transmembrane Transporter Activity PDZ Domain Binding Metal Ion Binding Calcium-transporting ATPase Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration	D-amino-acid Oxidase Activity Protein Binding Identical Protein Binding FAD Binding
	Biological Process	Negative Regulation Of Cytokine Production Regulation Of Vascular Associated Smooth Muscle Contraction Neural Retina Development Cellular Calcium Ion Homeostasis Brain Development Aging Regulation Of Blood Pressure Response To Cold Positive Regulation Of Bone Mineralization Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Calcium Ion Transport Cellular Response To Vitamin D Cellular Response To Corticosterone Stimulus Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Cellular Response To Insulin Stimulus Regulation Of Cardiac Conduction Calcium Ion Export Across Plasma Membrane	Proline Catabolic Process Protein Targeting To Peroxisome D-amino Acid Catabolic Process Cellular Nitrogen Compound Metabolic Process D-serine Catabolic Process Dopamine Biosynthetic Process D-alanine Catabolic Process D-serine Metabolic Process
Pathways		Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases	Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import
Drugs		Halothane Desflurane	3,4-Dihydro-2h-Pyrrolium-5-Carboxylate Imino-Tryptophan Flavin adenine dinucleotide D-Tryptophan Flavin-adenine dinucleotide-N5-isobutyl ketone Benzoic acid Anthranilic acid (2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID
Diseases
GWAS		Adult body size ( 32376654) Automobile speeding propensity ( 30643258) Biomedical quantitative traits ( 19396169) Blood pressure ( 24954895 21572416 24001895 21909110) Calcium levels ( 29403010) Chronotype ( 30696823) Coronary artery disease ( 32469254 29212778 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 22751097) Diastolic blood pressure ( 26390057 19430479 27841878 29403010 28739976 27618452 25249183 30487518) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure (long-term average) ( 28348047) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Diffusing capacity of carbon monoxide ( 30694715) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hypertension ( 31513605 31879980 19430479 25249183 28273873 30487518) Lumbar spine bone mineral density (integral) ( 27476799) Lumbar spine bone mineral density (trabecular) ( 27476799) Magnesium levels ( 20700443) Mean arterial pressure ( 26390057 29403010 27618448 30487518) Mean arterial pressure (long-term average) ( 28348047) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Morning person ( 30696823) Myocardial infarction ( 26343387) Nonobstructive coronary artery disease ( 26534935) Pulse pressure ( 26390057 27841878 29403010 28739976 30487518 30578418) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 30224653 26390057 19430479 27841878 29403010 28739976 27618447 27618452 25249183 30487518 30578418) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure (long-term average) ( 28348047) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Total body bone mineral density ( 29304378)	Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 32888494) Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
Interacting Genes		7 interacting genes: CALM1 CCR2 CSNK2A1 ERBIN F2RL1 PRKACA PRKCA	5 interacting genes: AOC1 DAOA EP300 PEX5 PRKAB2
Entrez ID		490	1610
HPRD ID		00158	15917
Ensembl ID		ENSG00000070961	ENSG00000110887
Uniprot IDs		A0A024RBC7 P20020	A0A024RBI1 P14920
PDB IDs		6A69	2DU8 2E48 2E49 2E4A 2E82 2GNZ 3CUK 3G3E 3W4I 3W4J 3W4K 3ZNN 3ZNO 3ZNP 3ZNQ 4QFC 4QFD 5ZJ9 5ZJA 6KBP
Enriched GO Terms of Interacting Partners?
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