NPY2R and PYY

Data Source:
HPRD (in vitro)

		NPY2R	PYY
Description		neuropeptide Y receptor Y2	peptide YY
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cilium Non-motile Cilium	Extracellular Region Extracellular Space
	Molecular Function	Peptide YY Receptor Activity Neuropeptide Y Receptor Activity Calcium Channel Regulator Activity Protein Binding Signaling Receptor Activity	G Protein-coupled Receptor Binding Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuropeptide Y Receptor Binding
	Biological Process	Behavioral Fear Response Positive Regulation Of Peptide Secretion Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Nitric Oxide Mediated Signal Transduction Aging Locomotory Behavior Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Nervous System Process Positive Regulation Of Dopamine Secretion Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Secretion Negative Regulation Of Secretion Regulation Of Sensory Perception Of Pain Negative Regulation Of Synaptic Transmission, Glutamatergic Negative Regulation Of Excitatory Postsynaptic Potential Negative Regulation Of Feeding Behavior	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Feeding Behavior Intestinal Epithelial Cell Differentiation
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Cysteamine Peptide YY (3-36) Obinepitide
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Premature menopause in childhood cancer survivors ( 29432556)	Blood protein levels ( 30072576) Diverticular disease ( 30177863) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Pulse pressure ( 28135244) Response to taxane treatment (placlitaxel) ( 23006423) Triglyceride levels ( 32203549)
Interacting Genes		4 interacting genes: NPY PYY RGS12 TRARG1	6 interacting genes: MEP1B NPY1R NPY2R NPY4R NPY5R SGTA
Entrez ID		4887	5697
HPRD ID		01216	02869
Ensembl ID		ENSG00000185149	ENSG00000131096
Uniprot IDs		P49146	P10082
PDB IDs		2IK3	2DEZ 2DF0 2L60 2NA5
Enriched GO Terms of Interacting Partners?
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