ATP2A1 and RNF167

Data Source:
BioGRID (two hybrid)

		ATP2A1	RNF167
Description		ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1	ring finger protein 167
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Platelet Dense Tubular Network Membrane Sarcoplasmic Reticulum Membrane Calcium Channel Complex	Cytoplasm Endomembrane System Integral Component Of Membrane
	Molecular Function	Calcium Transmembrane Transporter Activity, Phosphorylative Mechanism Calcium Ion Binding Protein Binding ATP Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism ATPase Activity Calcium-dependent ATPase Activity Protein Homodimerization Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Calcium Ion Transport Cellular Calcium Ion Homeostasis Apoptotic Mitochondrial Changes Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Ion Transmembrane Transport Response To Endoplasmic Reticulum Stress Positive Regulation Of Mitochondrial Calcium Ion Concentration Maintenance Of Mitochondrion Location Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Calcium Ion Import Calcium Ion Transmembrane Transport Relaxation Of Skeletal Muscle Positive Regulation Of Cardiac Muscle Cell Contraction Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Proton Transmembrane Transport Regulation Of Cardiac Conduction Calcium Ion Import Into Sarcoplasmic Reticulum	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle
Pathways		Pre-NOTCH Processing in Golgi Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases
Drugs		Enflurane Desflurane Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Tetrafluoroaluminate Ion 2,5-di-tert-butylhydroquinone (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE
Diseases		Brody myopathy
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 19079260 26961502 28892062 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Brain morphology (MOSTest) ( 32665545) Cannabis use ( 30150663) Crohn's disease ( 28067908) Extremely high intelligence ( 29520040) Hip circumference ( 31453325 25673412) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Lamb consumption ( 32066663) Type 2 diabetes ( 30297969) Waist circumference ( 31453325) Waist circumference variance ( 31453325) Weight ( 19079260)	Blood metabolite levels ( 24816252) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		8 interacting genes: APPL1 CCR8 IRS1 IRS2 PLN RNF167 SLN TULP3	17 interacting genes: ACTA1 AFG3L2 ATP2A1 CAPN3 MYH7 SLC22A18 SUMO1 TTN UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2K UBE2N UBE2W
Entrez ID		487	26001
HPRD ID		00157	15261
Ensembl ID		ENSG00000196296	ENSG00000108523
Uniprot IDs		O14983 Q7Z675	I3L0L6 Q9H6Y7
PDB IDs
Enriched GO Terms of Interacting Partners?
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