NPAS2 and NGLY1

Data Source:
BioGRID (two hybrid)

		NPAS2	NGLY1
Description		neuronal PAS domain protein 2	N-glycanase 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytosol CLOCK-BMAL Transcription Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Protein Dimerization Activity Hsp90 Protein Binding Sequence-specific Double-stranded DNA Binding	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Central Nervous System Development Circadian Rhythm Regulation Of Lipid Metabolic Process Circadian Regulation Of Gene Expression Response To Drug Positive Regulation Of DNA Repair Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Redox State Negative Regulation Of Cell Death Positive Regulation Of Behavioral Fear Response Regulation Of Response To DNA Damage Stimulus	Protein Folding Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Glycoprotein Catabolic Process Protein Deglycosylation
Pathways		BMAL1:CLOCK,NPAS2 activates circadian gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression Circadian Clock	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases
GWAS		Chronotype ( 30696823) Creutzfeldt-Jakob disease (variant) ( 22137330) Educational attainment ( 25201988) Intraocular pressure ( 31798171 31959993 30054594) Intraocular pressure and central corneal thickness (multi-trait analysis) ( 31798171) Metabolite levels ( 23823483) Platelet distribution width ( 32888494) Pulse pressure ( 27841878) White blood cell count ( 32888494)
Interacting Genes		30 interacting genes: ARNT2 ARNTL ARNTL2 BPIFA1 CLOCK CREBBP CRX CRY1 CRY2 CSNK2B DELEC1 EFS EP300 HESX1 HGS HSP90AA1 INCA1 KAT2B NCK2 NCOA3 NGLY1 RARA RASSF7 RHOXF1 RORC RPL6 RXRA TRAF4 UBAP2 ZSCAN1	18 interacting genes: APP BICRAL FAF1 GUCD1 NPAS2 NSFL1C PAX5 PAX6 RAD23A RAD23B SRPK2 TCF12 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP VMAC
Entrez ID		4862	55768
HPRD ID		09137	10118
Ensembl ID		ENSG00000170485	ENSG00000151092
Uniprot IDs		A2I2P5 Q99743	Q96IV0
PDB IDs			2CCQ 2CM0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?