NPY and ATP12A

Data Source:
BioGRID (two hybrid)

		NPY	ATP12A
Description		neuropeptide Y	ATPase H+/K+ transporting non-gastric alpha2 subunit
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Synapse Neuronal Dense Core Vesicle	Plasma Membrane Potassium:proton Exchanging ATPase Complex
	Molecular Function	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Signaling Receptor Binding Hormone Activity Neuropeptide Hormone Activity Calcium Channel Regulator Activity Protein Binding Neuropeptide Y Receptor Binding	P-type Sodium:potassium-exchanging ATPase Activity ATP Binding Potassium:proton Exchanging ATPase Activity Metal Ion Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Chemical Synaptic Transmission Feeding Behavior Regulation Of Blood Pressure Adult Feeding Behavior Central Nervous System Neuron Development Cerebral Cortex Development Neuron Projection Development Positive Regulation Of Appetite Intestinal Epithelial Cell Differentiation	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Proton Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	Ion transport by P-type ATPases
Drugs		Phentermine 2-aminoisobutyric acid L-tyrosinamide
Diseases
GWAS		Adult body size ( 32376654) Aggressive periodontitis (sex interaction) ( 25256105) Body size at age 10 ( 32376654) Chronotype ( 30696823) Morning person ( 30696823) Periodontitis ( 23459936) Vitamin D levels ( 25208829)	Diastolic blood pressure ( 30224653) Meconium ileus in cystic fibrosis ( 30807572) Obesity-related traits ( 23251661)
Interacting Genes		16 interacting genes: ATP12A BAG6 GHRL MC4R MEP1A MEP1B NPFF NPFFR2 NPY1R NPY2R NPY4R NPY5R NR1H2 PMCH UBQLN1 UBQLN2	3 interacting genes: GNAI3 NPY PPIB
Entrez ID		4852	479
HPRD ID		01214	01667
Ensembl ID		ENSG00000122585	ENSG00000075673
Uniprot IDs		A4D158 P01303	B4E0R9 P54707
PDB IDs		1QFA 1RON
Enriched GO Terms of Interacting Partners?
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