NID1 and PRELP

Data Source:
HPRD (in vitro)

		NID1	PRELP
Description		nidogen 1	proline and arginine rich end leucine rich repeat protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Space Golgi Lumen Extracellular Matrix Lysosomal Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Collagen Binding Laminin Binding Laminin-1 Binding Proteoglycan Binding	Extracellular Matrix Structural Constituent Heparin Binding Extracellular Matrix Structural Constituent Conferring Compression Resistance
	Biological Process	Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Glomerular Basement Membrane Development Basement Membrane Organization	Skeletal System Development Cell Aging Keratan Sulfate Biosynthetic Process Keratan Sulfate Catabolic Process
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Laminin interactions Laminin interactions	Keratan sulfate biosynthesis Keratan sulfate degradation Defective CHST6 causes MCDC1 Defective ST3GAL3 causes MCT12 and EIEE15 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Drugs		Urokinase
Diseases
GWAS		Cutaneous nevi ( 21478494) Diverticulitis ( 28585551) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Mean platelet volume ( 32888494) Response to levetiracetam in genetic generalized epilepsy ( 32308125) Urate levels in overweight individuals ( 25811787)	Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Blood protein levels ( 29875488)
Interacting Genes		21 interacting genes: APP COL13A1 COL1A1 COL4A1 FBLN1 FBLN2 FGA FGB HSPG2 ITGAV ITGB3 LACRT LAMA1 LAMC1 LAMC2 LGALS3BP PLAU PLXDC1 PRELP PTPRF SKIL	6 interacting genes: COL1A1 COL2A1 FBLN2 FN1 HSPG2 NID1
Entrez ID		4811	5549
HPRD ID		00574	03556
Ensembl ID		ENSG00000116962	ENSG00000188783
Uniprot IDs		P14543	P51888
PDB IDs		1NDX
Enriched GO Terms of Interacting Partners?
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