NFYC and PAX6

  • Data Source:
  • BioGRID (two hybrid)

NFYC

PAX6

Description nuclear transcription factor Y subunit gamma paired box 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Airway obstruction (FEV1/FVC<70%) in never smokers ( 30845926)
  • Airway obstruction (FEV1/FVC<lower limit of normal) in never smokers ( 30845926)
  • Depressive and manic episodes in bipolar disorder ( 26297903)
  • Platelet count ( 21507922)
  • Refractive error ( 32231278)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Body mass index ( 22344219 28892062)
  • Depression ( 29700475)
  • Diastolic blood pressure ( 27841878)
  • Feeling worry ( 29500382)
  • General factor of neuroticism ( 30867560)
  • Irritable mood ( 29500382)
  • Major depressive disorder ( 27479909)
  • Neurociticism ( 29500382)
  • Optic disc area ( 28073927)
  • Refractive error ( 32231278)
  • Systolic blood pressure ( 27841878)
Interacting Genes 67 interacting genes: ADGRF5 ADNP2 APOL4 ARID2 ATF6 ATF6B BDH2 BICRA BICRAL CEP76 CIART CIC CRX CSN2 CXorf38 DR1 DST ELF1 FAM168A GAPDH HGS HIVEP1 HSFY1 HSFY2 KLF11 KLF15 KLHDC7B LIN54 LMO4 MYC NFYA NFYB NUTM2F OSTF1 PAX4 PAX5 PAX6 POGZ POU3F2 POU6F1 POU6F2 PRR20A PRR20B PRR20C PRR20D PRR20E RAD52 SAE1 SMAD2 SMAD3 SMAP1 SNX2 SP1 SP2 SP4 SREBF2 STOX1 TAF11 TAF12 TAF6 TBP UBXN7 USF3 ZDHHC17 ZMYM6 ZNF34 ZSCAN1 126 interacting genes: ACOT12 AP1M1 ARIH2 ATP6V0D2 ATP6V1C2 BANP BCL2L15 C1orf109 C2CD6 CCDC103 CCDC6 CCL26 CDK3 CDX2 CGGBP1 CHAF1A CIB3 CINP CKS1B CSNK2A1 CTNNA3 CXorf38 DHPS DIAPH1 DLG1 DYNLL1 EAF1 EFHC1 EIF1AD EN1 EP300 ESRRG FAM50B GAS2L2 GCM2 GEMIN2 GPANK1 GRHL2 HGS HIPK2 HMBOX1 HMGB3 HNRNPC HOMER3 HOXA1 HOXB1 HOXC8 HOXC9 IPO13 KANK2 KCTD7 KRTAP9-3 KRTAP9-8 LARP4 LHX2 LNPK LONRF1 LXN LYSMD1 MAFG MAPRE1 MFAP1 MID1 MIPOL1 MISP MITF MORN3 MRPL53 NCDN NFKBID NFYC NGLY1 NKIRAS2 PATJ PBX1 PDE4C PICK1 PIN1 PKNOX1 POLR3C POLR3GL PPIL4 PRKAG1 PROX1 PSORS1C2 QRICH1 RANBP3 RAX RB1 RGS3 RNF111 SAE1 SEC14L4 SET SHANK3 SIGLEC6 SIX3 SLC12A8 SMARCA4 SOX10 SOX3 SPDYC SPG21 SRSF11 STAC SUMO1 TBP TCP11L1 THOC1 TLK1 TLK2 TRAPPC6A TRIM11 TRIP10 UBE2F UBE2K UBE3A UBXN2B UBXN7 USHBP1 VCX2 VSX2 WASHC3 ZBED1 ZNF124 ZNF410
Entrez ID 4802 5080
HPRD ID 05633 06167
Ensembl ID ENSG00000066136 ENSG00000007372
Uniprot IDs Q13952 A0A1W2PRA8 D1KF47 F1T0F8 P26367 Q66SS1
PDB IDs 1N1J 4AWL 4CSR 6QMP 6QMQ 6QMS 2CUE 6PAX
Enriched GO Terms of Interacting Partners?
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