NEK1 and ZNF350

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NEK1	ZNF350
Description		NIMA related kinase 1	zinc finger protein 350
Image			No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Centriolar Satellite	Nucleus Nucleoplasm Nuclear Matrix Nuclear Body Transcription Repressor Complex
	Molecular Function	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding 14-3-3 Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Cell Cycle Peptidyl-tyrosine Phosphorylation DNA Damage Response, Detection Of DNA Damage Cell Division Cilium Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway SUMOylation of transcription cofactors
Drugs		Fostamatinib
Diseases		Short rib-polydactyly syndrome
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Night sleep phenotypes ( 27126917) Schizophrenia ( 28991256 25056061 29483656) Supramarginal gyrus volume ( 31530798)	Tourette syndrome ( 30818990)
Interacting Genes		18 interacting genes: ATRX CSN2 CTNNAL1 EXOSC4 FEZ1 FEZ2 KIF3A LRRK1 LRRK2 MFHAS1 MRE11 PPP2R5A PTPRD SIRPA TP53BP1 TSC2 YWHAH ZNF350	6 interacting genes: ATF7IP BRCA1 FBXL17 NEK1 RNF11 USP21
Entrez ID		4750	59348
HPRD ID		06847	05663
Ensembl ID		ENSG00000137601	ENSG00000256683
Uniprot IDs		Q5JXL9 Q96PY6	Q9GZX5
PDB IDs		4APC 4B9D
Enriched GO Terms of Interacting Partners?
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