NDUFS1 and CFC1

Data Source:
BioGRID (affinity chromatography technology, proximity labelling technology)

		NDUFS1	CFC1
Description		NADH:ubiquinone oxidoreductase core subunit S1	cripto, FRL-1, cryptic family 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Respiratory Chain Complex I Mitochondrial Intermembrane Space Mitochondrial Matrix	Cellular_component Extracellular Region Plasma Membrane Cell Surface Anchored Component Of Membrane
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	Molecular_function Signaling Receptor Binding Nodal Binding Activin Receptor Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Apoptotic Mitochondrial Changes Mitochondrial Respiratory Chain Complex I Assembly Cellular Respiration ATP Metabolic Process Regulation Of Mitochondrial Membrane Potential Reactive Oxygen Species Metabolic Process	Blood Vessel Development Determination Of Left/right Symmetry Gastrulation Heart Development Anterior/posterior Pattern Specification Nodal Signaling Pathway Anatomical Structure Development
Pathways		Respiratory electron transport Complex I biogenesis	Signaling by NODAL Regulation of signaling by NODAL
Drugs		NADH
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome	Conotruncal heart malformations, including: Double-outlet right ventricle; Persistent truncus arteriosus; Conotruncal anomaly face syndrome Heterotaxy; Situs ambiguus
GWAS		Body mass index ( 26426971) Chronotype ( 30696823) Frontotemporal dementia with GRN mutation ( 29724592) Morning person ( 30696823)
Interacting Genes		5 interacting genes: C1QTNF9 CASP3 KDM1A MDH2 MDM2
Entrez ID		4719	55997
HPRD ID		01145	05548
Ensembl ID		ENSG00000023228	ENSG00000136698
Uniprot IDs		E5KRK5 P28331	A0A087WWV2 A0A087WX98 P0CG37
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?