NDUFS1 and C1QTNF9

Data Source:
BioGRID (two hybrid)

		NDUFS1	C1QTNF9
Description		NADH:ubiquinone oxidoreductase core subunit S1	C1q and TNF related 9
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Respiratory Chain Complex I Mitochondrial Intermembrane Space Mitochondrial Matrix	Extracellular Region Collagen Trimer
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	Hormone Activity Protein Binding Identical Protein Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Apoptotic Mitochondrial Changes Mitochondrial Respiratory Chain Complex I Assembly Cellular Respiration ATP Metabolic Process Regulation Of Mitochondrial Membrane Potential Reactive Oxygen Species Metabolic Process	Signal Transduction
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Body mass index ( 26426971) Chronotype ( 30696823) Frontotemporal dementia with GRN mutation ( 29724592) Morning person ( 30696823)
Interacting Genes		5 interacting genes: C1QTNF9 CASP3 KDM1A MDH2 MDM2	17 interacting genes: ACTC1 AMPD1 APPL1 CAPN3 DENND4A DST EIF4G2 GYG1 LARP4B MYBPC1 MYOM1 NAP1L1 NDUFS1 RDX TTN UTRN ZNF407
Entrez ID		4719	338872
HPRD ID		01145	14659
Ensembl ID		ENSG00000023228	ENSG00000240654
Uniprot IDs		E5KRK5 P28331	A0A3B0J259 P0C862
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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