NEB and XIRP2

Data Source:
BioGRID (two hybrid, pull down)

		NEB	XIRP2
Description		nebulin	xin actin binding repeat containing 2
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GO Annotations	Cellular Component	Cytosol Actin Cytoskeleton Z Disc Extracellular Exosome	Stress Fiber Focal Adhesion
	Molecular Function	Protein Binding Structural Constituent Of Muscle Actin Filament Binding	Actin Filament Binding
	Biological Process	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length Muscle Fiber Development Cardiac Muscle Thin Filament Assembly	Heart Development Biological_process Actin Cytoskeleton Organization
Pathways		Striated Muscle Contraction
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Nemaline myopathy
GWAS		Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598) Creatine kinase levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31451708) Letter-number span reordering ( 31596458) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Rapid automised naming of letters ( 30741946) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Squamous cell lung carcinoma ( 28604730)	Atopic dermatitis ( 25865352) Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Plasma renin activity levels ( 29650764)
Interacting Genes		24 interacting genes: ABI1 ACO1 ACTG2 ACTN4 AKTIP APC CALM1 DES ENO3 LIMS1 MTDH MYOM2 MYPN PTPN11 STRADB TMOD1 TMOD4 TPM1 TPM2 TRIM55 TRIM63 TTN XIRP1 XIRP2	5 interacting genes: DYSF FLNC LRRK2 NEB NEBL
Entrez ID		4703	129446
HPRD ID		01196	10267
Ensembl ID		ENSG00000183091	ENSG00000163092
Uniprot IDs		P20929 Q05C45 Q96MF8	A4UGR9
PDB IDs		1ARK 1NEB	4F14
Enriched GO Terms of Interacting Partners?
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