MYL2 and ZNF529

Data Source:
BioGRID (two hybrid)

		MYL2	ZNF529
Description		myosin light chain 2	zinc finger protein 529
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Actin Cytoskeleton Myosin Complex Myofibril Sarcomere A Band Cardiac Myofibril	Nucleus
	Molecular Function	Actin Monomer Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Regulation Of Striated Muscle Contraction Heart Development Muscle Filament Sliding Negative Regulation Of Cell Growth Cardiac Myofibril Assembly Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Positive Regulation Of The Force Of Heart Contraction	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Striated Muscle Contraction	Generic Transcription Pathway
Drugs
Diseases		Hypertrophic cardiomyopathy (HCM)
GWAS		Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Alcohol consumption (max-drinks) ( 29460428) Body mass index ( 24861553) Coffee consumption ( 29367735) Coronary heart disease ( 23364394) Drinking behavior ( 23364009) Gamma glutamyl transpeptidase ( 21909109) Glycemic traits ( 23575436) Gout ( 25646370) HDL cholesterol ( 21909109) HDL cholesterol levels ( 28334899) High density lipoprotein cholesterol levels ( 30718733) Metabolic syndrome ( 25705158) Metabolic syndrome (multivariate analysis) ( 29632305) Neutrophil count ( 29403010) Serum uric acid levels ( 32514006) Urate levels ( 31578528) White blood cell count ( 29403010)
Interacting Genes		12 interacting genes: CDC42BPA GJB5 LRSAM1 MYOC NHP2 PAK2 PKM PPP1R12C PSORS1C2 TRIM63 USP6 ZNF529	2 interacting genes: MYL2 SRPK2
Entrez ID		4633	57711
HPRD ID		01181	15821
Ensembl ID		ENSG00000111245	ENSG00000186020
Uniprot IDs		P10916 Q6IB42	A0A0C4DFR4 Q6P280
PDB IDs		5TBY
Enriched GO Terms of Interacting Partners?
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