AFDN and BCR

  • Data Source:
  • BioGRID (pull down, enzymatic study)
  • HPRD (two hybrid, in vitro)

AFDN

BCR

Description afadin, adherens junction formation factor BCR activator of RhoGEF and GTPase
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906)
Interacting Genes 37 interacting genes: BCR CTNNA1 EPHA7 EPHB2 EPHB3 EPHB6 F11R HRAS JAG1 LMO2 MRAS NECTIN1 NECTIN2 NECTIN3 NECTIN4 NRXN1 NRXN2 NRXN3 PFN1 PICK1 RALGDS RAP1A RAP1GAP RAP2A RIN1 RIT1 RIT2 RRAS RRAS2 SMAD2 SORBS1 SORBS2 SSX2IP TJP1 USP9X YWHAB YWHAG 45 interacting genes: ABL1 ABL2 AFDN APBA3 BLK CBL CDC42 CRK CRKL DLG1 DOK1 ERCC3 FES GRB10 GRB2 HCK HNF1A IGSF21 IRS1 JAK2 LNX1 MAP4K5 PLCG1 PTPN1 PTPN11 PTPN6 RAC1 RAD51 RASA1 RHOA SFN SHC1 SRC STUB1 TP53 TSG101 UBC UNC119 VAV1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID 4301 613
HPRD ID 01164 01044
Ensembl ID ENSG00000130396 ENSG00000186716
Uniprot IDs A8MQ02 G1UI22 J3KN01 P55196 P11274
PDB IDs 1T2M 1XZ9 2AIN 2EXG 5A6C 1K1F 2AIN 5N6R 5N7E 5OC7
Enriched GO Terms of Interacting Partners?
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