MFAP1 and DHX38

Data Source:
BioGRID (two hybrid)

		MFAP1	DHX38
Description		microfibril associated protein 1	DEAH-box helicase 38
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GO Annotations	Cellular Component	Microfibril Extracellular Region Nucleus Nucleoplasm U2-type Spliceosomal Complex Centrosome U2-type Precatalytic Spliceosome	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex Membrane Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding
	Biological Process	MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing
Pathways		Molecules associated with elastic fibres	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Blood protein levels ( 28240269 23696881) Cholesterol, total ( 25961943 20686565) Coronary artery disease ( 29212778) Depression ( 29700475) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) LDL cholesterol ( 25961943 20686565) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolite levels ( 22916037) Red blood cell count ( 32888494) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)
Interacting Genes		90 interacting genes: ALKBH8 AMOTL2 AP2M1 BEND7 BHLHB9 BICD2 CARD9 CCDC102B CCDC33 CCDC57 CDC14B CDCA7L CEP55 CEP57L1 CEP70 CEP76 COG6 COIL CSNK2A1 DHX38 DHX8 DNTTIP1 FAM9B FRA10AC1 FXR1 FXR2 GAS8 GKAP1 GOLGA2 GOLGA6L9 GRIPAP1 HMBOX1 HOMER3 HOOK2 HSF2BP HSPB1 IK KATNBL1 KIFC3 KLHL2 KRT40 L3MBTL3 LDOC1 LMNA LMNB2 LZTS1 MAD1L1 MCRS1 MID2 MIPOL1 MTUS2 NDC80 NGDN OLIG3 PAX6 PHC2 PIBF1 PIH1D1 PLEKHF2 SART1 SNW1 SSX2IP STAC3 STX11 TADA2A TCP10L TEPSIN TFIP11 THAP1 TLE5 TRAF2 TRIM41 TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB1 ZBTB14 ZBTB8A ZFP1 ZFP41 ZFP64 ZNF398 ZNF41 ZNF558 ZNF620 ZNF71 ZNF76 ZRANB1	8 interacting genes: CDC40 CSNK2A1 MFAP1 PPP4C SNRNP200 TERF2IP U2AF1 WBP4
Entrez ID		4236	9785
HPRD ID		02569	05720
Ensembl ID		ENSG00000140259	ENSG00000140829
Uniprot IDs		P55081	Q92620
PDB IDs		5F5S 5O9Z 6AHD	5YZG 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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