RAB8A and PDE6D

Data Source:
HPRD (two hybrid)

		RAB8A	PDE6D
Description		RAB8A, member RAS oncogene family	phosphodiesterase 6D
Image
GO Annotations	Cellular Component	Golgi Membrane Endosome Centrosome Centriole Cytosol Plasma Membrane Cilium Synaptic Vesicle Postsynaptic Density Trans-Golgi Network Transport Vesicle Midbody Phagocytic Vesicle Membrane Trans-Golgi Network Membrane Neuronal Cell Body Dendritic Spine Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Non-motile Cilium Glutamatergic Synapse	Cytoplasm Cytosol Cytoskeleton Cilium Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Kinase Binding Small GTPase Binding Myosin V Binding	GTPase Inhibitor Activity Protein Binding Small GTPase Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Autophagy Axonogenesis Protein Secretion Regulation Of Autophagy Regulation Of Exocytosis Cellular Response To Insulin Stimulus Post-translational Protein Modification Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Vesicle Fusion To Target Membrane Regulation Of Protein Transport Cilium Assembly Protein Localization To Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse	Visual Perception Negative Regulation Of GTPase Activity Response To Stimulus
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	ARL13B-mediated ciliary trafficking of INPP5E RAS processing
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 27863252) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494) Red cell distribution width ( 32888494)	Eating disorders (purging via substances) ( 23568457) Height ( 18391951)
Interacting Genes		23 interacting genes: BAG6 BIRC6 GDI2 IKBKG MAP4K2 MDM2 MYO5C OCRL ODF2 OPTN PDE6D PQBP1 RAB11A RAB13 RAB3IL1 RAB3IP RABIF RIMS2 RPH3A RPH3AL SYTL1 SYTL4 TFRC	25 interacting genes: ARL15 ARL16 ARL2 ARL3 CDC42 CETN3 FAM219A GNAI1 GRK1 GRK7 HRAS OTP PTGIR RAB13 RAB18 RAB8A RAD23A RAP1A RAP2B RASA1 RHEB RHOA RHOB RND1 RPGR
Entrez ID		4218	5147
HPRD ID		01296	04056
Ensembl ID		ENSG00000167461	ENSG00000156973
Uniprot IDs		A0A024R7I3 P61006	B8ZZK5 O43924 Q6IB24
PDB IDs		3QBT 3TNF 4LHV 4LHW 4LHX 4LHY 4LHZ 4LI0 5SZI 6RIR 6SQ2 6STF 6STG 6ZSI 6ZSJ	1KSG 1KSH 1KSJ 3T5G 3T5I 4JHP 4JV6 4JV8 4JVB 4JVF 5E80 5E8F 5F2U 5ML2 5ML3 5ML4 5ML6 5ML8 5NAL 5TAR 5TB5 5X72 5X73 5X74 5YAV 5YAW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?