ART3 and ALCAM

Data Source:
BioGRID (two hybrid)

		ART3	ALCAM
Description		ADP-ribosyltransferase 3 (inactive)	activated leukocyte cell adhesion molecule
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Extracellular Exosome	Immunological Synapse Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Axon Dendrite Intrinsic Component Of Plasma Membrane T Cell Receptor Complex Neuronal Cell Body Extracellular Exosome
	Molecular Function	NAD+ ADP-ribosyltransferase Activity NAD+-protein-arginine ADP-ribosyltransferase Activity NADP+-protein-arginine ADP-ribosyltransferase Activity	Signaling Receptor Binding Protein Binding Identical Protein Binding
	Biological Process	Protein ADP-ribosylation Peptidyl-arginine ADP-ribosylation	Adaptive Immune Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Motor Neuron Axon Guidance Retinal Ganglion Cell Axon Guidance Axon Extension Involved In Axon Guidance Neuron Projection Extension
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	L1CAM interactions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Hippocampal volume ( 29274321)	Adult body size ( 32376654) Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576 29875488) Body mass index ( 25673413) Breast cancer ( 31757997) Chronotype ( 30696823) Cortical surface area (visual PC2) ( 32198502) Erectile dysfunction in type 1 diabetes ( 22704111) Glomerular filtration rate in chronic kidney disease ( 26420894) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Initial pursuit acceleration ( 29064472) Intraocular pressure ( 29617998) Irritable mood ( 29500382) Metabolite levels ( 23823483) Ovarian disease with few adhesions ( 28333195) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Visceral fat ( 30942860)
Interacting Genes		2 interacting genes: ALCAM PRKCD	3 interacting genes: ART3 CD6 EGFR
Entrez ID		419	214
HPRD ID		04363	03389
Ensembl ID		ENSG00000156219	ENSG00000170017
Uniprot IDs		Q13508	B3KNN9 Q13740
PDB IDs			1KJC 5A2F
Enriched GO Terms of Interacting Partners?
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