MAGEA3 and IQSEC1

Data Source:
BioGRID (two hybrid)

		MAGEA3	IQSEC1
Description		MAGE family member A3	IQ motif and Sec7 domain ArfGEF 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum	Nucleolus Synaptic Vesicle Postsynaptic Density Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Caspase Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding
	Biological Process	Negative Regulation Of Protein Processing Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Keratinocyte Migration Dendritic Spine Development Positive Regulation Of Focal Adhesion Disassembly
Pathways
Drugs
Diseases
GWAS			Body mass index ( 26426971) Periodontitis (DPAL) ( 24024966) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		16 interacting genes: ACOT7 BCL7B C17orf49 CINP DNM1L ENOX2 EXOC5 HLA-DRB1 HTT IQSEC1 KIF27 LSM2 PCYT1A RUSC1 S100A9 STAMBPL1	2 interacting genes: APOE MAGEA3
Entrez ID		4102	9922
HPRD ID		02166	11052
Ensembl ID		ENSG00000221867	ENSG00000144711
Uniprot IDs		P43357	A0A0C4DGT3 B4DGC5 Q6DN90
PDB IDs		1QEW 4V0P 5BRZ	3QWM 4C0A 5NLV 5NLY 6FNE
Enriched GO Terms of Interacting Partners?
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