SMAD3 and AR

  • Data Source:
  • HPRD (in vitro, in vivo)

SMAD3

AR

Description SMAD family member 3 androgen receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 282 interacting genes: AATF ACTB AKT1 ANAPC10 ANK3 APMAP APOB APP AR ARHGEF6 ATF2 ATF3 AXIN1 AXIN2 BLZF1 BPTF BRCA1 BRCA2 BTRC CAMK2G CCDC198 CCDC33 CDC16 CDC25A CDC27 CDK2 CDK4 CDK8 CDK9 CEBPA CEBPB CEBPD CFDP1 CFH CFLAR CHRD CLASRP CORO1A CPSF7 CPTP CREBBP CRX CSH2 CSNK1D CSNK1G2 CTCF CTNNB1 CUL1 CXXC5 CYP11A1 DAB2 DACH1 DDX5 DEDD DNAJB4 DNAJB5 DNMT3L DVL1 E2F4 E2F5 EBI3 EID2 EIF4B EIF4ENIF1 EP300 EPAS1 EPB41 ERBIN ESR1 ESR2 ETS1 FAM90A1 FBLN1 FHL2 FHL3 FLI1 FLNA FOS FOXG1 FOXH1 FOXO1 FOXO3 FOXO4 GGA1 GIT2 GLI3 GMEB1 GSC GSK3B GTF2IRD1 HDAC1 HDAC4 HDAC5 HEY1 HEYL HGS HIF1A HIPK2 HIVEP1 HMGA2 HNF4A HNRNPK HOXC11 HP HSPA4 HYAL2 IL37 ISL1 ITCH JPH3 JUN JUNB JUND KANSL1 KAT2B KDM2A KMT2B KPNB1 KRT10 KRT2 LBP LCK LEF1 LEMD3 LMNA MAGI2 MAP3K7 MAPK1 MAPK14 MAPK8 MAPK9 MAX MBD1 MCM3AP MDM4 MECOM MED15 MEN1 MEOX2 MTF2 MYC MYD88 MYO5B MYOCD MYOD1 NCOA6 NEDD4 NEDD4L NEDD9 NFIA NFYC NOTCH1 NOTCH4 NR3C1 NR4A1 NUP153 NUP214 OTUB1 PAEP PAPPA PARD3 PARP4 PAX8 PCDH1 PCK2 PEX6 PHC2 PIAS2 PIAS3 PIAS4 PIK3CA PIN1 PLAG1 PLAGL1 PLG PML PPM1A PPP1R12C PPP2R1A PRDM4 PRKAR1B PRKAR2A PROX1 PRTN3 PSMB1 PSMD11 RAB38 RANBP9 RARG RASD2 RASL12 RBL1 RBPMS RBX1 RCVRN RELA RIOK2 RIT1 RNF111 RNF31 RPA1 RPLP0 RRAS2 RUNX2 RUNX3 S100A4 SAP130 SBK3 SERTAD1 SETD2 SF3A1 SF3B2 SIN3A SKI SKIL SKOR2 SMAD1 SMAD2 SMAD4 SMAD7 SMAD9 SMURF1 SMURF2 SNRNP70 SNW1 SP1 SPTBN1 SQSTM1 SREBF2 SRY SS18L1 ST6GALNAC2 STRAP STUB1 SVEP1 TANK TDP2 TEKT4 TF TFE3 TGFBR1 TGFBR2 TGIF1 TGIF2 TGM2 TLE5 TLR4 TMED1 TOB1 TP53 TP73 TPM3 TRIM33 TSC2 TSC22D4 UBQLN4 UCHL5 USP7 VDR VIM VSIR WEE1 WWP1 WWP2 XPO6 XRCC6 YBX1 YY1 ZBTB16 ZBTB3 ZC3H12A ZCCHC14 ZDHHC4 ZEB1 ZEB2 ZFYVE9 ZMYM2 ZMYND11 ZNF329 ZNF774 ZNF8 ZNF83 265 interacting genes: ABL1 ABL2 ACTB AHR AKT1 APOL2 APPBP2 ARID5A ATF2 BAG1 BLK BLNK BRCA1 BTK CACUL1 CALM1 CALR CASP1 CASP3 CASP7 CASP8 CAV1 CCAR2 CCND1 CCNE1 CCNH CDC25A CDC25B CDC37 CDK1 CDK6 CDK7 CDK9 CEBPA CEBPB CHD8 COX5B CREBBP CRK CTDSP2 CTNNB1 CUL4B DAP3 DAXX DCAF6 DCC DDB2 DDC DENND5A EED EFCAB6 EGFR ELF3 EP300 ERCC2 ERCC3 ESR1 ETV5 EZH2 FES FGR FHL2 FLNA FOXA1 FOXG1 FOXO1 GADD45GIP1 GAK GAPDH GLI2 GRAP2 GRB2 GRB7 GRIP1 GSK3B GSN GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 HCK HDAC1 HDAC3 HDAC4 HIF1A HIPK3 HMGB1 HMGB2 HOTAIR HSH2D HSP90AA1 IARS1 IDE IFI16 IL6ST INPPL1 JMJD1C JUN KAT2B KAT5 KAT7 KDM1A KIF1A KIFAP3 KLK2 LCK LCOR LYN MAGEA11 MAPK1 MATK MDM2 MDN1 MED1 MED12L MED14 MED24 MLH3 MYBBP1A MYLIP NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOR1 NCOR2 NDE1 NELFCD NFKB1 NISCH NLRP10 NONO NR0B1 NR0B2 NR2C1 NR2C2 NR3C1 NR3C2 NR5A1 NRIP1 NSD1 NSD2 PA2G4 PAK6 PELP1 PIAS1 PIAS2 PIAS3 PIAS4 PIK3R1 PIK3R2 PIK3R3 PLCG1 PLCG2 PNRC1 PNRC2 POU2F1 POU2F2 POU5F1 PRKG1 PRMT1 PRPF6 PSMC3IP PTEN PTK6 PTPN11 PXN RAC3 RACK1 RAD54L2 RAD9A RAF1 RAN RANBP9 RASA1 RB1 RBAK RCHY1 REL RELA REPS2 RNASEL RNF14 RNF4 RNF6 RUNX1 RUNX2 SART3 SFPQ SH2D1A SH2D1B SH2D2A SH2D3C SH3YL1 SHB SHC1 SHC3 SHC4 SHE SIRT1 SLC25A4 SMAD1 SMAD3 SMAD4 SMARCA2 SMARCA4 SMARCD1 SMARCE1 SOCS3 SOCS6 SP1 SPDEF SPOP SRC SREBF1 SRY STAP1 STAT3 STUB1 SUMO1 SUV39H2 SVIL SYK TADA3 TAF1 TBP TCF20 TCF4 TCF7L2 TDG TGFB1I1 TGIF1 TLE5 TMF1 TNK2 TNS1 TNS4 TPD52 TRIM24 TRIP4 TSG101 TXNDC5 UBE2I UBE3A USP10 UXT VAV1 VAV2 VAV3 VCP VHL WIPI1 XRCC5 XRCC6 YES1 YWHAQ ZBTB1 ZBTB16 ZBTB32 ZBTB7A ZMIZ1 ZMIZ2 ZNF451
Entrez ID 4088 367
HPRD ID 04380 02437
Ensembl ID ENSG00000166949 ENSG00000169083
Uniprot IDs A0A024R5Z3 P84022 Q9P0T0 A0A087WUX9 F1D8N5 G4VV16 P10275 Q9NUA2
PDB IDs 1MHD 1MJS 1MK2 1OZJ 1U7F 2LAJ 2LB2 5OD6 5ODG 5XOC 6ZMN 1E3G 1GS4 1T5Z 1T63 1T65 1XJ7 1XOW 1XQ3 1Z95 2AM9 2AMA 2AMB 2AO6 2AX6 2AX7 2AX8 2AX9 2AXA 2HVC 2OZ7 2PIO 2PIP 2PIQ 2PIR 2PIT 2PIU 2PIV 2PIW 2PIX 2PKL 2PNU 2Q7I 2Q7J 2Q7K 2Q7L 2YHD 2YLO 2YLP 2YLQ 2Z4J 3B5R 3B65 3B66 3B67 3B68 3BTR 3L3X 3L3Z 3RLJ 3RLL 3V49 3V4A 3ZQT 4HLW 4K7A 4OEA 4OED 4OEY 4OEZ 4OFR 4OFU 4OGH 4OH5 4OH6 4OHA 4OIL 4OIU 4OJ9 4OJB 4OK1 4OKB 4OKT 4OKW 4OKX 4OLM 4QL8 5CJ6 5JJM 5T8E 5T8J 5V8Q 5VO4
Enriched GO Terms of Interacting Partners?
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