MARCKS and NMT1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		MARCKS	NMT1
Description		myristoylated alanine rich protein kinase C substrate	N-myristoyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Plasma Membrane Focal Adhesion Cell Cortex Actin Cytoskeleton Actin Filament Bundle Germinal Vesicle Extracellular Exosome	Cytoplasm Mitochondrion Cytosol Plasma Membrane Extrinsic Component Of Membrane
	Molecular Function	Protein Kinase C Binding Calmodulin Binding Identical Protein Binding Actin Filament Binding	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding Myristoyltransferase Activity
	Biological Process	Actin Filament Organization Central Nervous System Development Actin Filament Bundle Assembly Actin Crosslink Formation	In Utero Embryonic Development N-terminal Protein Myristoylation N-terminal Peptidyl-glycine N-myristoylation Regulation Of Rhodopsin Mediated Signaling Pathway Cellular Ketone Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways		Acetylcholine regulates insulin secretion	Late Phase of HIV Life Cycle Inactivation, recovery and regulation of the phototransduction cascade Activation, myristolyation of BID and translocation to mitochondria
Drugs			(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone
Diseases
GWAS		Bipolar disorder (body mass index interaction) ( 24322204) Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308) Household income ( 31844048) Household income (MTAG) ( 31844048) Type 2 diabetes ( 25760438)	Asthma ( 31619474) Blood glucose levels ( 31928498) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Multisite chronic pain ( 31194737) Periventricular white matter hyperintensities ( 32517579) Plateletcrit ( 32888494) Pulse pressure ( 30578418) Systolic blood pressure ( 31928498 30578418) White matter hyperintensities ( 32358547)
Interacting Genes		14 interacting genes: CALM2 CCNE1 CDK1 CDK2 CDK4 CTSB NMT1 PKN1 PRKCA PRKCB PRKCZ RHOU SPP1 TOB1	15 interacting genes: ACBD6 ANXA13 ARL5A CABP1 CABP2 CAPN2 CSNK2A1 FYN GNAZ HPCA LYN MARCKS NOS3 SRC TP53
Entrez ID		4082	4836
HPRD ID		07519	01187
Ensembl ID		ENSG00000277443	ENSG00000136448
Uniprot IDs		P29966 Q6NVI1	P30419
PDB IDs			1RXT 3IU1 3IU2 3IWE 3JTK 4C2Y 4C2Z 5MU6 5NPQ 5O6H 5O6J 5O9S 5O9T 5O9U 5O9V 5UUT 6EHJ 6F56 6FZ2 6FZ3 6FZ5 6PAV 6QRM 6SJZ 6SK2 6SK3 6SK8 6SKJ
Enriched GO Terms of Interacting Partners?
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