MIR92A1 and P3H1

Data Source:
BioGRID (unspecified method)

		MIR92A1	P3H1
Description		microRNA 92a-1	prolyl 3-hydroxylase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Extracellular Vesicle	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Protein-containing Complex Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	Molecular_function Iron Ion Binding Protein Binding Collagen Binding Procollagen-proline 3-dioxygenase Activity L-ascorbic Acid Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Acute Inflammatory Response Regulation Of Heart Contraction Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Necrotic Cell Death Negative Regulation Of Angiogenesis Positive Regulation Of Interleukin-6 Production Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Smooth Muscle Cell Apoptotic Process Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Apoptotic Process Positive Regulation Of JUN Kinase Activity Negative Regulation Of JUN Kinase Activity Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of JNK Cascade Negative Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Cellular Response To Fatty Acid Cellular Response To Low-density Lipoprotein Particle Stimulus Positive Regulation Of Monocyte Chemotactic Protein-1 Production Cellular Stress Response To Acid Chemical Vascular Endothelial Cell Response To Fluid Shear Stress Blood Vessel Diameter Maintenance Negative Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Sprouting Angiogenesis Positive Regulation Of Metalloendopeptidase Activity Negative Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Positive Regulation Of Endothelial Cell Activation Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell	Protein Folding Negative Regulation Of Cell Population Proliferation Positive Regulation Of Neuron Projection Development Protein Hydroxylation Peptidyl-proline Hydroxylation Collagen Metabolic Process Regulation Of Protein Secretion Protein Stabilization Bone Development Chaperone-mediated Protein Folding Negative Regulation Of Post-translational Protein Modification
Pathways			Collagen biosynthesis and modifying enzymes
Drugs			Ascorbic acid Proline
Diseases			Osteogenesis imperfecta
GWAS
Interacting Genes		76 interacting genes: ADARB1 C1QBP CELF1 CPSF1 CPSF2 CPSF6 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LRPPRC MATR3 MSI2 NOL6 NONO NUDT21 P3H1 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 QARS1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 WWP2 YBX1 YBX3	13 interacting genes: CDC42 MIR1-2 MIR107 MIR141 MIR18B MIR19A MIR19B1 MIR9-3 MIR92A1 MIRLET7A2 MIRLET7B MIRLET7I SLC2A4
Entrez ID		407048	64175
HPRD ID			11227
Ensembl ID		ENSG00000283705	ENSG00000117385
Uniprot IDs			Q32P28
PDB IDs
Enriched GO Terms of Interacting Partners?
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