MIR29A and USP36

Data Source:
BioGRID (unspecified method)

		MIR29A	USP36
Description		microRNA 29a	ubiquitin specific peptidase 36
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Mitochondrion Extracellular Exosome Extracellular Vesicle	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Angiogenesis Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of Collagen Biosynthetic Process Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Apoptotic Process Regulation Of DNA Methylation Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Circulating Fibrinogen Levels Positive Regulation Of Wound Healing Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Ubiquitin-dependent Protein Catabolic Process Nucleolus Organization Negative Regulation Of Macroautophagy Histone Deubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Regulation Of Protein Stability Regulation Of Apoptotic Process Protein Stabilization Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Protein Targeting To Mitochondrion Regulation Of RRNA Processing
Pathways
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Keratinocyte cancer (MTAG) ( 31174203) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Pancreatic cancer ( 25086665) Red blood cell count ( 32888494) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White blood cell count ( 32888494)	Atrial fibrillation ( 30061737) Diverticular disease ( 30177863) Heel bone mineral density ( 30598549) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 31928498 30578418)
Interacting Genes		84 interacting genes: AIMP2 APOBEC3B AQR C1QBP CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 RARS1 RBFOX2 RBM14 RBM4 RBM45 RBM47 RBMS1 RBMS2 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TIAL1 TRA2B TRIM25 TRIM71 UPF1 USP36 UTP20 YBX1 YBX3 ZC3H7A ZC3H7B ZNF346	16 interacting genes: H2BC3 MIR128-1 MIR138-2 MIR15B MIR16-1 MIR17 MIR19B2 MIR21 MIR29A MIR29C MIR34B MIR7-1 MYC SRPK2 TRIM26 UBC
Entrez ID		407021	57602
HPRD ID			07164
Ensembl ID		ENSG00000284032	ENSG00000055483
Uniprot IDs			A0A024R8V6 Q9P275
PDB IDs
Enriched GO Terms of Interacting Partners?
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