MIR222 and ESRP1

Data Source:
BioGRID (unspecified method)

		MIR222	ESRP1
Description		microRNA 222	epithelial splicing regulatory protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Vesicle	Nucleus Nucleoplasm Nuclear Body Ribonucleoprotein Complex
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding MRNA Binding Protein Binding
	Biological Process	Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Angiogenesis Negative Regulation Of Interleukin-21 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Apoptotic Process Negative Regulation By Host Of Viral Genome Replication Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Axon Regeneration Negative Regulation Of Inflammatory Response Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cell Adhesion Molecule Production Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Schwann Cell Migration Negative Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Positive Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration Negative Regulation Of Cardiac Muscle Cell Differentiation	MRNA Processing RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Regulation Of RNA Splicing
Pathways			Signaling by BRAF and RAF fusions FGFR2 alternative splicing
Drugs
Diseases
GWAS			Abstraction and mental flexibility ( 31596458) Urate levels ( 31578528)
Interacting Genes		75 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LIN28A LRPPRC MATR3 MSI2 NONO PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PURA QARS1 RBFOX2 RBM14 RBM4 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	45 interacting genes: ARID5A ATXN1 DAZAP2 KLHDC7B KRTAP19-5 MED25 MIR106A MIR106B MIR128-2 MIR138-1 MIR138-2 MIR141 MIR155 MIR15B MIR19B1 MIR19B2 MIR200A MIR200C MIR20B MIR21 MIR222 MIR25 MIR29C MIR34A MIR34B MIR363 MIR7-1 MIR9-1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7F2 MIRLET7G MIRLET7I OXER1 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2
Entrez ID		407007	54845
HPRD ID			07881
Ensembl ID		ENSG00000207725	ENSG00000104413
Uniprot IDs			A0A2U3TZN9 Q6NXG1
PDB IDs			2DHA 2RVJ
Enriched GO Terms of Interacting Partners?
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