MIR200C and DDX23

Data Source:
BioGRID (unspecified method)

		MIR200C	DDX23
Description		microRNA 200c	DEAD-box helicase 23
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm U5 SnRNP Nucleolus U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding
	Biological Process	Negative Regulation Of Cytokine Production Positive Regulation Of Neuron Projection Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Interleukin-33 Production Negative Regulation Of Neuron Death Response To Amyloid-beta Regulation Of Vascular Endothelial Cell Proliferation Positive Regulation Of Mesodermal Cell Differentiation	Cis Assembly Of Pre-catalytic Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing R-loop Disassembly
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Interacting Genes		89 interacting genes: AIMP2 AQR ATXN2L C1QBP CHERP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM56 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	25 interacting genes: ERG MIR106B MIR128-1 MIR138-2 MIR141 MIR143 MIR19B2 MIR200B MIR200C MIR214 MIR25 MIR363 MIR429 MIR7-1 MIR7-2 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7E MIRLET7G MIRLET7I PCM1 TERF1 TERF2IP WBP4
Entrez ID		406985	9416
HPRD ID			09908
Ensembl ID		ENSG00000207713	ENSG00000174243
Uniprot IDs			A0A024R0Z3 B3KY11 Q9BUQ8
PDB IDs			3JCR 4NHO 6AH0 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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