MIR15B and CSTF3

Data Source:
BioGRID (unspecified method)

		MIR15B	CSTF3
Description		microRNA 15b	cleavage stimulation factor subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Vesicle	Nucleus Nucleoplasm
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding MRNA Binding Protein Binding
	Biological Process	Branching Involved In Blood Vessel Morphogenesis Cardiac Muscle Hypertrophy Negative Regulation Of Cell Population Proliferation Negative Regulation Of Angiogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Apoptotic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Translation Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Inflammatory Response Negative Regulation Of Wound Healing Negative Regulation Of Trophoblast Cell Migration Negative Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage RNA 3'-end Processing MRNA 3'-end Processing
Pathways			mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Malaria ( 31844061)	Anger ( 24489884) Non-response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		102 interacting genes: ADARB1 AIMP1 APOBEC3B AQR ATXN2L C1QBP CELF1 CPSF1 CSTF3 DARS1 DCP1A DCP1B DCP2 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC3 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT21 NUFIP2 PATL1 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RBM45 RBMS2 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	13 interacting genes: CSTF1 CSTF2 MIR128-2 MIR138-2 MIR15B MIR19A MIR19B1 MIR21 MIR92A2 MIRLET7A3 MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		406949	1479
HPRD ID			02651
Ensembl ID		ENSG00000207779	ENSG00000176102
Uniprot IDs			Q12996
PDB IDs			6B3X 6URO
Enriched GO Terms of Interacting Partners?
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