MIRLET7F2 and SFPQ

Data Source:
BioGRID (unspecified method)

		MIRLET7F2	SFPQ
Description		microRNA let-7f-2	splicing factor proline and glutamine rich
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm Nuclear Matrix Nuclear Speck Dendrite Cytoplasm Paraspeckles RNA Polymerase II Transcription Regulator Complex
	Molecular Function		Transcription Regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding
	Biological Process	Gene Silencing By MiRNA	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Double-strand Break Repair Via Homologous Recombination Activation Of Innate Immune Response Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Innate Immune Response Positive Regulation Of Sister Chromatid Cohesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Histone H3 Deacetylation Dendritic Transport Of Messenger Ribonucleoprotein Complex Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways			PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis
Drugs			Copper Artenimol
Diseases
GWAS		Bipolar disorder ( 31043756)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Endometrial cancer ( 21499250) Hip circumference ( 28552196)
Interacting Genes		95 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CPSF1 CPSF2 CPSF6 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TENT2 TRA2B TRIM71 TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	103 interacting genes: APBB1 AR CSNK2A1 ERG ESR1 EXOSC5 FHL2 FUS GAS7 H3-4 JPT1 LAMTOR5 LINC01554 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NONO PIN1 PPARG PPP1CA PRPF40A PSPC1 PTBP1 RAC1 SIN3A SMAD5 SNRPA SREK1 TCERG1 TOP1 UBC UBE2I WBP4 ZMYM2
Entrez ID		406889	6421
HPRD ID			07284
Ensembl ID		ENSG00000208012	ENSG00000116560
Uniprot IDs			A0A384N5Z8 P23246 Q86VG2
PDB IDs			4WII 4WIJ 4WIK 5WPA 6NCQ 6OWJ
Enriched GO Terms of Interacting Partners?
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