MIRLET7E and CRTAP

Data Source:
BioGRID (unspecified method)

		MIRLET7E	CRTAP
Description		microRNA let-7e	cartilage associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Protein-containing Complex
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	Protein Binding Collagen Binding
	Biological Process	Negative Regulation Of Interleukin-6 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Signaling Receptor Activity	Spermatogenesis Peptidyl-proline Hydroxylation To 3-hydroxy-L-proline Collagen Fibril Organization Protein Stabilization Chaperone-mediated Protein Folding Negative Regulation Of Post-translational Protein Modification
Pathways			Collagen biosynthesis and modifying enzymes
Drugs
Diseases			Osteogenesis imperfecta
GWAS			Asthma ( 31959851 31619474) Major depressive disorder ( 29317602) Multiple sclerosis ( 31604244) Refractive error ( 32231278) Retinal detachment or retinal break ( 31816047)
Interacting Genes		105 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PLRG1 PRMT1 PTBP1 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RBM47 RBM5 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346	24 interacting genes: MIR1-1 MIR10B MIR128-1 MIR138-2 MIR140 MIR16-1 MIR16-2 MIR17 MIR18A MIR199A2 MIR19A MIR19B1 MIR200B MIR200C MIR20A MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIRLET7B MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		406887	10491
HPRD ID			16110
Ensembl ID		ENSG00000198972	ENSG00000170275
Uniprot IDs			O75718
PDB IDs
Enriched GO Terms of Interacting Partners?
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