MIRLET7A3 and PURB

Data Source:
BioGRID (unspecified method)

		MIRLET7A3	PURB
Description		microRNA let-7a-3	purine rich element binding protein B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm
	Molecular Function		RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Transcription Factor Binding Purine-rich Negative Regulatory Element Binding SMAD Binding
	Biological Process	Gene Silencing By MiRNA	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell Population Proliferation Cell Differentiation Regulation Of Myeloid Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Platelet count ( 27863252)
Interacting Genes		100 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CPSF1 CPSF2 CSTF1 CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 TRMT10C U2SURP UPF1 UTP20 YBX1 YBX3 ZFR ZNF346	22 interacting genes: AP1M1 CSNK2A1 IL7R LNX1 MBD2 MIR128-1 MIR128-2 MIR25 MIR29C MIR31 MIR34B MIR363 MIR7-1 MIR7-3 MIR9-2 MIRLET7A3 MIRLET7G MIRLET7I NABP1 PCDHB14 PURA ZNF497
Entrez ID		406883	5814
HPRD ID			12325
Ensembl ID		ENSG00000283990	ENSG00000146676
Uniprot IDs			Q96QR8
PDB IDs
Enriched GO Terms of Interacting Partners?
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