LTBR and TRAF5

  • Data Source:
  • HPRD (in vitro, in vivo)

LTBR

TRAF5

Description lymphotoxin beta receptor TNF receptor associated factor 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Ankylosing spondylitis ( 23749187)
  • Basophil count ( 32888494)
  • Celiac disease ( 31591516)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 26192919 28067908)
  • Eosinophil percentage of white cells ( 32888494)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Inflammatory bowel disease ( 28067908)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
  • Multiple sclerosis ( 31604244 24076602)
  • Platelet distribution width ( 32888494)
  • Plateletcrit ( 32888494 27863252)
  • Primary biliary cirrhosis ( 22961000)
  • Tonsillectomy ( 27182965 28928442)
  • White blood cell count ( 32888494)
Interacting Genes 15 interacting genes: BIRC2 DIABLO HES1 LTA LTB MTNR1B RABAC1 TNFSF14 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRIM37 ZMYND11 66 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 CDC37 CIB3 COG7 COMMD3 DGKH ENOX2 FAM9A FBXO28 GAS8 GOLGA2 GORASP2 HOMER1 HSD17B10 HSF2BP LMO4 LNX1 LTBR MAP3K14 MAP3K5 MDM2 MEOX2 NMI NTAQ1 NUMBL ODF2 PIAS2 PIBF1 PICK1 PSMA1 RAD23A RIPK1 RIPK2 RNF111 RNF4 SDCBP SEC13 SERPINB9 SUMO1 TBK1 TDP2 THAP1 THAP7 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 YPEL5 ZFAND6 ZNF655
Entrez ID 4055 7188
HPRD ID 02988 03834
Ensembl ID ENSG00000111321 ENSG00000082512
Uniprot IDs P36941 O00463
PDB IDs 1RF3 4MXW
Enriched GO Terms of Interacting Partners?
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