LTA4H and TMEM62

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LTA4H	TMEM62
Description		leukotriene A4 hydrolase	transmembrane protein 62
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytosol Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Integral Component Of Membrane
	Molecular Function	RNA Binding Aminopeptidase Activity Epoxide Hydrolase Activity Leukotriene-A4 Hydrolase Activity Protein Binding Peptidase Activity Zinc Ion Binding Tripeptide Aminopeptidase Activity Metalloaminopeptidase Activity	Hydrolase Activity
	Biological Process	Proteolysis Leukotriene Metabolic Process Leukotriene Biosynthetic Process Long-chain Fatty Acid Biosynthetic Process Peptide Catabolic Process Neutrophil Degranulation Cellular Protein Metabolic Process
Pathways		Synthesis of Leukotrienes (LT) and Eoxins (EX) Neutrophil degranulation Biosynthesis of D-series resolvins Biosynthesis of protectins Biosynthesis of E-series 18(S)-resolvins Biosynthesis of aspirin-triggered D-series resolvins Biosynthesis of E-series 18(R)-resolvins
Drugs		Captopril N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine 3-(Benzyloxy)Pyridin-2-Amine Imidazole Ubenimex DG051 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole N-(pyridin-3-ylmethyl)aniline (4-fluorophenyl)(pyridin-4-yl)methanone 1-(2,2'-bithiophen-5-yl)methanamine N-[4-(benzyloxy)phenyl]glycinamide (2S)-2-amino-5-oxo-5-[(4-phenylmethoxyphenyl)amino]pentanoic acid 4-amino-N-[4-(benzyloxy)phenyl]butanamide N-methyl-1-(2-thiophen-2-ylphenyl)methanamine {4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone (R)-pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanol 1-(4-thiophen-2-ylphenyl)methanamine N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline 4-(2-amino-1,3-thiazol-4-yl)phenol Kelatorphan 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol Tosedostat
Diseases
GWAS		Blood protein levels ( 30072576) Diffusing capacity of carbon monoxide ( 30694715) Height ( 20966902) Refractive error ( 32231278) Small intestine neuroendocrine tumor ( 27492634) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		3 interacting genes: ARPC3 TINF2 TMEM62	8 interacting genes: APEH CSE1L F2RL1 HSPA5 LTA4H PTPN6 SLC27A6 ZNF287
Entrez ID		4048	80021
HPRD ID		01056	08669
Ensembl ID		ENSG00000111144	ENSG00000137842
Uniprot IDs		A0A140VK27 P09960	Q0P6H9
PDB IDs		1GW6 1H19 1HS6 1SQM 2R59 2VJ8 3B7R 3B7S 3B7T 3B7U 3CHO 3CHP 3CHQ 3CHR 3CHS 3FH5 3FH7 3FH8 3FHE 3FTS 3FTU 3FTV 3FTW 3FTX 3FTY 3FTZ 3FU0 3FU3 3FU5 3FU6 3FUD 3FUE 3FUF 3FUH 3FUI 3FUJ 3FUK 3FUL 3FUM 3FUN 3U9W 4DPR 4L2L 4MKT 4MS6 4R7L 4RSY 4RVB 5AEN 5BPP 5FWQ 5N3W 5NI2 5NI4 5NI6 5NIA 5NID 5NIE 6ENB 6ENC 6END 6O5H
Enriched GO Terms of Interacting Partners?
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