CUEDC1 and WBP2

Data Source:
BioGRID (two hybrid)

		CUEDC1	WBP2
Description		CUE domain containing 1	WW domain binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Estrogen Receptor Binding Chromatin DNA Binding
	Biological Process		Response To Progesterone Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen Establishment Of Protein Localization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Positive Regulation Of Histone H3-K14 Acetylation
Pathways
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494) Multiple sclerosis--Brain Glutamate Levels ( 20802204) Tenofovir clearance in HIV infection ( 26148204)	Adult body size ( 32376654) Platelet count ( 32888494) Red blood cell count ( 32888494) White matter hyperintensities ( 32358547)
Interacting Genes		17 interacting genes: ABI2 IKBKG LRRK2 MAP3K1 MFHAS1 NCK2 NEDD4 NEDD4L NTAQ1 OSTF1 SMARCD1 SMURF1 SMURF2 UBC UBE2D2 UBE2E2 WBP2	54 interacting genes: ANAPC1 ANKRD13A ANKRD13D ARCN1 BAG3 CCT7 CLEC4G COPA COPB1 COPB2 COPE COPG1 CUEDC1 DDX17 EEF1B2 EPN2 ESR1 GRPEL1 H4C1 HOMER3 HUWE1 ITCH KRT18 KRT8 KRT9 LGALS8 MAGEA4 MAGI1 MYO6 NEDD4 NEDD4L PAX8 POLH RHBDD3 RNF168 RPS27A RPS3 SDHA SEPTIN3 SMAD5 TDP2 TOLLIP TOM1L2 UBA52 UBC UBE2D3 UBE2E3 UBE3A UBQLN1 UIMC1 WWP1 WWP2 WWTR1 YAP1
Entrez ID		404093	23558
HPRD ID		13098	06097
Ensembl ID		ENSG00000180891	ENSG00000132471
Uniprot IDs		Q6AHX0 Q9NWM3	A0A024R8L1 Q969T9
PDB IDs		2DHY
Enriched GO Terms of Interacting Partners?
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