C14orf180 and LIME1

Data Source:
BioGRID (two hybrid)

		C14orf180	LIME1
Description		chromosome 14 open reading frame 180	Lck interacting transmembrane adaptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Space Integral Component Of Membrane B Cell Receptor Complex
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding
	Biological Process		Adaptive Immune Response Regulation Of Transcription By RNA Polymerase II Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of MAP Kinase Activity T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of NIK/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Rheumatoid arthritis ( 30891314)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462) Inflammatory bowel disease ( 28067908 23128233) Meat-related diet ( 32066663) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)
Interacting Genes		45 interacting genes: AQP3 AQP6 ASZ1 BIK CD74 CD79A CISD2 CLEC7A CPLX4 CYBC1 EBAG9 ERGIC3 FAM174A FAM209A GPR152 GPRC5D GPX8 HAS3 KASH5 KCNJ6 LHFPL5 LIME1 MFF MFSD14B MGST3 MUC1 NCR3LG1 PDZK1IP1 PPP1CB PPP1CC REEP4 SAR1A SLC35C2 TEX29 TIMMDC1 TM4SF19 TMEM106C TMEM14B TMEM167B TMEM207 TMEM31 TMEM51 TMEM80 VSIR ZDHHC15	46 interacting genes: AGR3 AIG1 AQP1 ARFGAP3 BNIP2 C14orf180 CALN1 CIAO2A CLN6 EMD FRMD8 GAD2 GOSR2 GRB2 LCK LHFPL5 LPAR3 LYN MAN2B2 MEST MIEF2 NDRG4 NINJ1 PBX3 PKMYT1 PLCG2 PNPO PTPN9 RTP2 SEC22C SLC41A2 SNAP47 SNX1 STX6 STX7 TBRG4 TMBIM6 TMEM143 TMEM243 TMEM74 TMEM86B TMEM97 TRAF3IP3 UNC93B1 UPK2 ZFPL1
Entrez ID		400258	54923
HPRD ID		17383	07904
Ensembl ID		ENSG00000184601	ENSG00000203896
Uniprot IDs		A0A024R6Q4 B4DN93 J3KNP8 Q8N912	A0A087WT39 Q9H400
PDB IDs
Enriched GO Terms of Interacting Partners?
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