ARHGDIG and MED10

Data Source:
BioGRID (two hybrid)

		ARHGDIG	MED10
Description		Rho GDP dissociation inhibitor gamma	mediator complex subunit 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle	Ubiquitin Ligase Complex Chromatin Nucleoplasm Mediator Complex
	Molecular Function	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Blastocyst Hatching Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Protein Localization Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Rho GTPase cycle	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		12 interacting genes: AGTR1 BICRAL CDC42 CEP170P1 KXD1 MED10 RAC1 RHOA RHOB RHOG RHOH TACC3	12 interacting genes: ABI2 ARHGDIG ESR1 ESR2 FUCA1 HNF4A KDM4B MOB4 NAP1L1 PEBP1 SYCE1L TRIM45
Entrez ID		398	84246
HPRD ID		04163	14680
Ensembl ID		ENSG00000242173	ENSG00000133398
Uniprot IDs		F1T0H7 Q99819	Q9BTT4
PDB IDs
Enriched GO Terms of Interacting Partners?
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