LHCGR and CHST9

Data Source:
HPRD (in vitro)

		LHCGR	CHST9
Description		luteinizing hormone/choriogonadotropin receptor	carbohydrate sulfotransferase 9
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Integral Component Of Plasma Membrane	Golgi Membrane Extracellular Region Integral Component Of Membrane
	Molecular Function	Luteinizing Hormone Receptor Activity G Protein-coupled Peptide Receptor Activity Choriogonadotropin Hormone Receptor Activity Choriogonadotropin Hormone Binding	N-acetylgalactosamine 4-O-sulfotransferase Activity Sulfotransferase Activity
	Biological Process	Ovarian Follicle Development G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Male Gonad Development Hormone-mediated Signaling Pathway Ovulation Cycle Process Male Genitalia Development Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Luteinizing Hormone Signaling Pathway Cognition Cellular Response To Gonadotropin Stimulus Cellular Response To Luteinizing Hormone Stimulus	Sulfur Compound Metabolic Process Carbohydrate Biosynthetic Process Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Biosynthetic Process Hormone Biosynthetic Process
Pathways		Hormone ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Goserelin Menotropins Lutropin alfa Cetrorelix Choriogonadotropin alfa Buserelin Chorionic Gonadotropin (Human)
Diseases		46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS) Premature ovarian failure Precocious puberty, including: Central precocious puberty (CEPREPU); Familial male precocious puberty (FMPP)
GWAS		Body mass index ( 28892062) Laterality in neovascular age-related macular degeneration ( 28775256) Polycystic ovary syndrome ( 22885925 21151128) Sex hormone-binding globulin levels ( 22829776) Triglyceride levels ( 32154731)	Blood protein levels ( 30072576 29875488) Breast cancer ( 29059683 23535729) Bronchopulmonary dysplasia ( 23897914) Dental caries ( 23259602) Metabolite levels ( 23823483) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
Interacting Genes		11 interacting genes: ARRB2 CANX CGA CGB3 CHST9 GIPC1 GNAI2 GNAS LHB SLC9A3R1 TSHR	1 interacting genes: LHCGR
Entrez ID		3973	83539
HPRD ID		01073	13058
Ensembl ID		ENSG00000138039	ENSG00000154080
Uniprot IDs		P22888	A0A024RC28 Q7L1S5
PDB IDs		1LUT 1XUL
Enriched GO Terms of Interacting Partners?
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