ARHGDIA and SDHC

Data Source:
BioGRID (two hybrid)

		ARHGDIA	SDHC
Description		Rho GDP dissociation inhibitor alpha	succinate dehydrogenase complex subunit C
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Membrane Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone) Integral Component Of Membrane Respiratory Chain Complex II
	Molecular Function	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding	Succinate Dehydrogenase Activity Protein Binding Electron Transfer Activity Heme Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Rho Protein Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Negative Regulation Of Axonogenesis Positive Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Semaphorin-plexin Signaling Pathway Regulation Of Actin Cytoskeleton Reorganization	Tricarboxylic Acid Cycle Mitochondrial Electron Transport, Succinate To Ubiquinone Aerobic Respiration
Pathways		Axonal growth inhibition (RHOA activation) Rho GTPase cycle Axonal growth stimulation	Respiratory electron transport Citric acid cycle (TCA cycle)
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases
GWAS			Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		41 interacting genes: ACTL6A ADRB2 ATXN3 BAK1 CASP3 CASP7 CBX5 CDC42 CDKN1B EP300 FEN1 HAAO HDAC6 HERPUD1 IKBKG JUP KAT2B MAPK6 NEDD4L POT1 RAC1 RAC2 RAC3 RDX RHOA RHOG RHOH SDHC SH3GL3 SIRT2 ST3GAL4 SUMO4 TERF1 TINF2 TRIM13 TWF2 UBE2I UBE2L6 UBE2R2 UFM1 VAV1	3 interacting genes: ARHGDIA MDM2 XRCC6
Entrez ID		396	6391
HPRD ID		03565	03878
Ensembl ID		ENSG00000141522	ENSG00000143252
Uniprot IDs		J3QQX2 P52565 V9HWE8	A0A0S2Z4B7 A0A0S2Z4C9 Q99643
PDB IDs		1CC0 1FSO 1FST 1FT0 1FT3 1HH4 1KMT 1QVY 1RHO 2BXW 2JHS 2JHT 2JHU 2JHV 2JHW 2JHX 2JHY 2JHZ 2JI0 2N80
Enriched GO Terms of Interacting Partners?
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