LGALS3 and LGALS3BP

Data Source:
HPRD (in vitro, in vivo)

		LGALS3	LGALS3BP
Description		galectin 3	galectin 3 binding protein
Image
GO Annotations	Cellular Component	Immunological Synapse Extracellular Region Extracellular Space Nucleus Spliceosomal Complex Cytoplasm Mitochondrial Inner Membrane Plasma Membrane Cell Surface Membrane Secretory Granule Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Ficolin-1-rich Granule Membrane	Extracellular Region Extracellular Space Membrane Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	RNA Binding Protein Phosphatase Inhibitor Activity Protein Binding IgE Binding Protein Phosphatase Binding Carbohydrate Binding Chemoattractant Activity Laminin Binding	Scavenger Receptor Activity Protein Binding
	Biological Process	Monocyte Chemotaxis MRNA Processing RNA Splicing Neutrophil Chemotaxis Epithelial Cell Differentiation Positive Regulation Of Protein-containing Complex Assembly Regulation Of T Cell Proliferation Neutrophil Degranulation Innate Immune Response Regulation Of Myeloid Cell Differentiation Negative Regulation Of Endocytosis Eosinophil Chemotaxis Macrophage Chemotaxis Negative Regulation Of T Cell Receptor Signaling Pathway Positive Chemotaxis Regulation Of T Cell Apoptotic Process Mononuclear Cell Migration Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Calcium Ion Import Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Protein Tyrosine Phosphatase Activity Negative Regulation Of Immunological Synapse Formation Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Positive Regulation Of Dendritic Cell Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Platelet Degranulation Endocytosis Cellular Defense Response Cell Adhesion Signal Transduction
Pathways		Neutrophil degranulation Advanced glycosylation endproduct receptor signaling RUNX1 regulates transcription of genes involved in differentiation of myeloid cells RUNX2 regulates genes involved in differentiation of myeloid cells	Platelet degranulation
Drugs		2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide Lactose
Diseases
GWAS		Blood protein levels ( 30072576 28240269) Blood protein levels in cardiovascular risk ( 28369058) Leukoderma in response to rhododendrol ( 32558222) Protein biomarker ( 23056639) Testicular germ cell tumor ( 28604728)	Blood protein levels ( 30072576)
Interacting Genes		28 interacting genes: APP C1GALT1C1 CRX CSNK1A1 CSNK2A1 CSNK2A2 CUBN CYHR1 ELN FCGR2A GEMIN4 GOLGA2 INCA1 KIF16B LGALS3BP LIM2 MCPH1 MEFV MMP2 MYOC PPIG PRR13 SS18L1 SUFU TRIM17 TRIM22 TRIM23 TRIM6	22 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1
Entrez ID		3958	3959
HPRD ID		01090	02796
Ensembl ID		ENSG00000131981	ENSG00000108679
Uniprot IDs		A0A024R693 P17931	A0A0S2Z3Y1 Q08380
PDB IDs		1A3K 1KJL 1KJR 2NMN 2NMO 2NN8 2XG3 3AYA 3AYC 3AYD 3AYE 3T1L 3T1M 3ZSJ 3ZSK 3ZSL 3ZSM 4BLI 4BLJ 4BM8 4JC1 4JCK 4LBJ 4LBK 4LBL 4LBM 4LBN 4LBO 4R9A 4R9B 4R9C 4R9D 4RL7 4XBN 5E88 5E89 5E8A 5EXO 5H9P 5H9R 5IUQ 5NF7 5NF9 5NFA 5NFB 5NFC 5OAX 5ODY 6B8K 6EOG 6EOL 6EXY 6EYM 6F2Q 6F6Y 6FK2 6FOF 6G0V 6H64 6I74 6I75 6I76 6I77 6I78 6KXA 6KXB 6Q0Q 6Q17 6QGE 6QGF 6QLN 6QLO 6QLP 6QLQ 6QLR 6QLS 6QLT 6QLU 6RHL 6RHM 6RZF 6RZG 6RZH 6RZI 6RZJ 6RZK 6RZL 6RZM 6Y4C 6Y78	1BY2 6GFB
Enriched GO Terms of Interacting Partners?
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