LGALS1 and LGALS3BP

Data Source:
HPRD (in vivo, in vitro)

		LGALS1	LGALS3BP
Description		galectin 1	galectin 3 binding protein
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Lumen Cytosol Cell Surface Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Space Membrane Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	RNA Binding Protein Binding Carbohydrate Binding Lactose Binding Identical Protein Binding Laminin Binding	Scavenger Receptor Activity Protein Binding
	Biological Process	Plasma Cell Differentiation Apoptotic Process Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Neuron Projection Development T Cell Costimulation Positive Regulation Of Erythrocyte Aggregation Response To Isolation Stress Response To Drug Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Post-translational Protein Modification Cellular Protein Metabolic Process Myoblast Differentiation Positive Regulation Of Viral Entry Into Host Cell Response To Axon Injury Cellular Response To Glucose Stimulus Cellular Response To Organic Cyclic Compound Positive Regulation Of Dendritic Cell Differentiation	Platelet Degranulation Endocytosis Cellular Defense Response Cell Adhesion Signal Transduction
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Platelet degranulation
Drugs		Mercaptoethanol Thiodigalactoside 1,4-Dithiothreitol Artenimol
Diseases
GWAS		Fat distribution (HIV) ( 21897333)	Blood protein levels ( 30072576)
Interacting Genes		17 interacting genes: CD2 CD4 CD7 CD8A CDC42 GEMIN4 HRAS HSPB2 ITGB1 LGALS3BP MUC16 NLGN3 PTEN PTPRC SPN USP4 VPREB1	22 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1
Entrez ID		3956	3959
HPRD ID		01040	02796
Ensembl ID		ENSG00000100097	ENSG00000108679
Uniprot IDs		A0A384MR27 P09382	A0A0S2Z3Y1 Q08380
PDB IDs		1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83	1BY2 6GFB
Enriched GO Terms of Interacting Partners?
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